AIMC Topic: Positron Emission Tomography Computed Tomography

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Prediction of PD-L1 expression in NSCLC patients using PET/CT radiomics and prognostic modelling for immunotherapy in PD-L1-positive NSCLC patients.

Clinical radiology
AIM: To develop a positron emission tomography/computed tomography (PET/CT)-based radiomics model for predicting programmed cell death ligand 1 (PD-L1) expression in non-small cell lung cancer (NSCLC) patients and estimating progression-free survival...

Predictive models of epidermal growth factor receptor mutation in lung adenocarcinoma using PET/CT-based radiomics features.

Medical physics
BACKGROUND: Lung adenocarcinoma (LAC) comprises a substantial subset of non-small cell lung cancer (NSCLC) diagnoses, where epidermal growth factor receptor (EGFR) mutations play a pivotal role as indicators for therapeutic intervention with targeted...

Uncertainty-aware deep learning for segmentation of primary tumor and pathologic lymph nodes in oropharyngeal cancer: Insights from a multi-center cohort.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
PURPOSE: Information on deep learning (DL) tumor segmentation accuracy on a voxel and a structure level is essential for clinical introduction. In a previous study, a DL model was developed for oropharyngeal cancer (OPC) primary tumor (PT) segmentati...

Development and validation of pan-cancer lesion segmentation AI-model for whole-body 18F-FDG PET/CT in diverse clinical cohorts.

Computers in biology and medicine
BACKGROUND: This study develops a deep learning-based automated lesion segmentation model for whole-body 3DF-fluorodeoxyglucose (FDG)-Position emission tomography (PET) with computed tomography (CT) images agnostic to disease location and site.

PET and CT based DenseNet outperforms advanced deep learning models for outcome prediction of oropharyngeal cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND: In the HECKTOR 2022 challenge set [1], several state-of-the-art (SOTA, achieving best performance) deep learning models were introduced for predicting recurrence-free period (RFP) in head and neck cancer patients using PET and CT images.

Machine learning models for enhanced diagnosis and risk assessment of prostate cancer with Ga-PSMA-617 PET/CT.

European journal of radiology
OBJECTIVE: Prostate cancer (PCa) is highly heterogeneous, making early detection of adverse pathological features crucial for improving patient outcomes. This study aims to predict PCa aggressiveness and identify radiomic and protein biomarkers assoc...

The Role of AI in Lymphoma: An Update.

Seminars in nuclear medicine
Malignant lymphomas encompass a range of malignancies with incidence rising globally, particularly with age. In younger populations, Hodgkin and Burkitt lymphomas predominate, while older populations more commonly experience subtypes such as diffuse ...

Impact of [F]FDG PET/CT Radiomics and Artificial Intelligence in Clinical Decision Making in Lung Cancer: Its Current Role.

Seminars in nuclear medicine
Lung cancer remains one of the most prevalent cancers globally and the leading cause of cancer-related deaths, accounting for nearly one-fifth of all cancer fatalities. Fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography ([F]FDG...

Preoperative Maximum Standardized Uptake Value Emphasized in Explainable Machine Learning Model for Predicting the Risk of Recurrence in Resected Non-Small Cell Lung Cancer.

JCO clinical cancer informatics
PURPOSE: To comprehensively analyze the association between preoperative maximum standardized uptake value (SUV) on 18F-fluorodeoxyglucose positron emission tomography-computed tomography and postoperative recurrence in resected non-small cell lung c...