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Positron-Emission Tomography

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Differentiating IDH status in human gliomas using machine learning and multiparametric MR/PET.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: The purpose of this study was to develop a voxel-wise clustering method of multiparametric magnetic resonance imaging (MRI) and 3,4-dihydroxy-6-[F]-fluoro-L-phenylalanine (FDOPA) positron emission tomography (PET) images using an unsuperv...

Restoration of amyloid PET images obtained with short-time data using a generative adversarial networks framework.

Scientific reports
Our purpose in this study is to evaluate the clinical feasibility of deep-learning techniques for F-18 florbetaben (FBB) positron emission tomography (PET) image reconstruction using data acquired in a short time. We reconstructed raw FBB PET data of...

Low-dose PET image noise reduction using deep learning: application to cardiac viability FDG imaging in patients with ischemic heart disease.

Physics in medicine and biology
INTRODUCTION: Cardiac [F]FDG-PET is widely used for viability testing in patients with chronic ischemic heart disease. Guidelines recommend injection of 200-350 MBq [F]FDG, however, a reduction of radiation exposure has become increasingly important,...

Translating amyloid PET of different radiotracers by a deep generative model for interchangeability.

NeuroImage
It is challenging to compare amyloid PET images obtained with different radiotracers. Here, we introduce a new approach to improve the interchangeability of amyloid PET acquired with different radiotracers through image-level translation. Deep genera...

Deep learning-based metal artefact reduction in PET/CT imaging.

European radiology
OBJECTIVES: The susceptibility of CT imaging to metallic objects gives rise to strong streak artefacts and skewed information about the attenuation medium around the metallic implants. This metal-induced artefact in CT images leads to inaccurate atte...

Cerebral blood flow measurements with O-water PET using a non-invasive machine-learning-derived arterial input function.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Cerebral blood flow (CBF) can be measured with dynamic positron emission tomography (PET) of O-labeled water by using tracer kinetic modelling. However, for quantification of regional CBF, an arterial input function (AIF), obtained from arterial bloo...

Deep learning-based T1-enhanced selection of linear attenuation coefficients (DL-TESLA) for PET/MR attenuation correction in dementia neuroimaging.

Magnetic resonance in medicine
PURPOSE: The accuracy of existing PET/MR attenuation correction (AC) has been limited by a lack of correlation between MR signal and tissue electron density. Based on our finding that longitudinal relaxation rate, or R , is associated with CT Hounsfi...

Sub-2 mm depth of interaction localization in PET detectors with prismatoid light guide arrays and single-ended readout using convolutional neural networks.

Medical physics
PURPOSE: Depth of interaction (DOI) readout in PET imaging has been researched in efforts to mitigate parallax error, which would enable the development of small diameter, high-resolution PET scanners. However, DOI PET has not yet been commercialized...

Automatic rat brain image segmentation using triple cascaded convolutional neural networks in a clinical PET/MR.

Physics in medicine and biology
The purpose of this work was to develop and evaluate a deep learning approach for automatic rat brain image segmentation of magnetic resonance imaging (MRI) images in a clinical PET/MR, providing a useful tool for analyzing studies of the pathology a...

Artificial intelligence enables whole-body positron emission tomography scans with minimal radiation exposure.

European journal of nuclear medicine and molecular imaging
PURPOSE: To generate diagnostic F-FDG PET images of pediatric cancer patients from ultra-low-dose F-FDG PET input images, using a novel artificial intelligence (AI) algorithm.