AIMC Topic: Predictive Value of Tests

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Predicting drug metabolism and pharmacokinetics features of in-house compounds by a hybrid machine-learning model.

Drug metabolism and pharmacokinetics
We constructed machine learning-based pharmacokinetic prediction models with very high performance. The models were trained on 26138 and 16613 compounds involved in metabolic stability and cytochrome P450 inhibition, respectively. Because the compoun...

Application of deep learning to establish a diagnostic model of breast lesions using two-dimensional grayscale ultrasound imaging.

Clinical imaging
PURPOSE: There are currently few specific artificial intelligence (AI) studies for Breast Imaging Reporting and Data System (BI-RADS) category 4A lesions. This study aimed to establish an AI diagnostic model of breast lesions using two-dimensional gr...

Prospective assessment of breast cancer risk from multimodal multiview ultrasound images via clinically applicable deep learning.

Nature biomedical engineering
The clinical application of breast ultrasound for the assessment of cancer risk and of deep learning for the classification of breast-ultrasound images has been hindered by inter-grader variability and high false positive rates and by deep-learning m...

Alberta Stroke Program Early CT Score Calculation Using the Deep Learning-Based Brain Hemisphere Comparison Algorithm.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
OBJECTIVES: The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is a promising tool for the evaluation of stroke expansion to determine suitability for reperfusion therapy. The aim of this study was to validate deep learning-based AS...

Machine Learning Algorithms for Predicting Fatty Liver Disease.

Annals of nutrition & metabolism
BACKGROUND: Fatty liver disease (FLD) has become a rampant condition. It is associated with a high rate of morbidity and mortality in a population. The condition is commonly referred as FLD. Early prediction of FLD would allow patients to take necess...

Long-term mortality risk stratification of liver transplant recipients: real-time application of deep learning algorithms on longitudinal data.

The Lancet. Digital health
BACKGROUND: Survival of liver transplant recipients beyond 1 year since transplantation is compromised by an increased risk of cancer, cardiovascular events, infection, and graft failure. Few clinical tools are available to identify patients at risk ...