Text mining of scientific libraries and social media has already proven itself as a reliable tool for drug repurposing and hypothesis generation. The task of mapping a disease mention to a concept in a controlled vocabulary, typically to the standard...
This paper presents a robust 3D point cloud registration algorithm based on bidirectional Maximum Correntropy Criterion (MCC). Comparing with traditional registration algorithm based on the mean square error (MSE), using the MCC is superior in dealin...
BACKGROUND: Identifying new potential treatment options for medical conditions that cause human disease burden is a central task of biomedical research. Since all candidate drugs cannot be tested with animal and clinical trials, in vitro approaches a...
International journal of occupational safety and ergonomics : JOSE
May 9, 2018
This study aimed at establishing fault tree analysis (FTA) using expert opinion to compute the probability of an event. To find the probability of the top event (TE), all probabilities of the basic events (BEs) should be available when the FTA is dra...
Statistical methods in medical research
May 2, 2018
Data-adaptive methods have been proposed to estimate nuisance parameters when using doubly robust semiparametric methods for estimating marginal causal effects. However, in the presence of near practical positivity violations, these methods can produ...
Computer methods and programs in biomedicine
Apr 28, 2018
BACKGROUND AND OBJECTIVE: In medical examinations doctors use various techniques in order to provide to the patients an accurate analysis of their actual state of health. One of the commonly used methodologies is the x-ray screening. This examination...
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Mar 14, 2018
BACKGROUND: We developed machine-learning (ML) models to estimate a patient's risk of cardiac death based on adenosine myocardial perfusion SPECT (MPS) and associated clinical data, and compared their performance to baseline logistic regression (LR)....
Computer methods and programs in biomedicine
Jan 31, 2018
BACKGROUND AND OBJECTIVE: Automatic detection and classification of the masses in mammograms are still a big challenge and play a crucial role to assist radiologists for accurate diagnosis. In this paper, we propose a novel Computer-Aided Diagnosis (...
Interdisciplinary sciences, computational life sciences
Jan 30, 2018
Interaction of multiple genetic variants is a major challenge in the development of effective treatment strategies for complex disorders. Identifying the most promising genes enhances the understanding of the underlying mechanisms of the disease, whi...
Proceedings of the National Academy of Sciences of the United States of America
Jan 22, 2018
Prevention and early intervention are the most effective ways of avoiding or minimizing psychological, physical, and financial suffering from cancer. However, such proactive action requires the ability to predict the individual's susceptibility to ca...
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