AIMC Topic: Prognosis

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Preoperative plasma ceramide profiling coupled with machine learning accurately predicts recurrence of hepatocellular carcinoma after resection.

Lipids in health and disease
BACKGROUND: Accurate stratification of recurrence risk after curative resection remains a critical challenge in the management of hepatocellular carcinoma (HCC). Dysregulated ceramide (CER) metabolism has been implicated in HCC progression and relaps...

Mortality risk prediction in NSTE-ACS following PCI: Insights from a real-world cohort.

PloS one
BACKGROUND: Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) is a major contributor to cardiovascular mortality, yet reliable tools for individualized mortality prediction remain limited. Machine learning offers the potential to enhance pr...

Predictive variables analysis for the tongue crib treatment of anterior crossbite in mixed dentition.

BMC oral health
OBJECTIVE: This study aimed to identify key prognostic variables and to develop and validate a clinical prediction model for pre-treatment assessment of tongue crib applicability.

Assessing the accuracy of survival machine learning and traditional statistical models for Alzheimer's disease prediction over time: a study on the ADNI cohort.

BMC medical research methodology
BACKGROUND: Mild cognitive impairment (MCI) represents a transitional stage to Alzheimer's disease (AD), making progression prediction crucial for timely intervention. Predictive models integrating clinical, laboratory, and survival data can enhance ...

Machine learning models predict mortality risk in diabetic neuropathy patients using MIMIC-IV data.

Scientific reports
We aimed to construct and validate interpretable models for predicting mortality risk using machine learning (ML) methods to identify the risk factors associated with mortality in patients with diabetic neuropathy (DN). We selected patients from the ...

Development of a diagnostic model for ovarian cancer based on machine learning algorithms and functional analysis of key biomarker SOX17.

Journal of ovarian research
BACKGROUND: Ovarian cancer (OC) demonstrates the poorest prognosis among gynecological malignancies, with five-year survival rates below 45%, primarily due to late-stage diagnosis. To address this challenge, we systematically identified OC-specific d...

Development and validation of an interpretable machine learning model for early prediction in patients with diabetes and sepsis.

Scientific reports
We aimed to identify and validate key predictive factors influencing 28-day survival rates in patients with diabetes and sepsis and to develop a predictive model based on these factors to assist clinical decision-making. In this retrospective cohort ...

Prognostic prediction in soft-tissue sarcomas using deep learning and digital pathology of tumor and margin areas.

Scientific reports
The histological FNCLCC grade is the primary prognostic factor in soft-tissue sarcoma (STS) but fails to fully capture high risk patients. This study aimed to develop and validate a deep learning (DL) model to predict metastatic relapse-free survival...

Construction and validation of an anoikis-related prognostic model for lung adenocarcinoma based on bulk and single-cell transcriptomic data.

PloS one
Lung adenocarcinoma (LUAD) is a highly aggressive lung cancer with poor prognosis due to lack of reliable biomarkers. Resistance to anoikis drives tumor progression and metastasis. This study aims to develop and validate an anoikis-related prognostic...