With a clinical trial failure rate of 99.6% for Alzheimer's Disease (AD), early diagnosis is critical. Machine learning (ML) models have shown promising results in early AD prediction, with survival ML models outperforming typical classifiers by prov...
Computer methods and programs in biomedicine
39368442
BACKGROUND: The long-term survival of liver transplant (LT) recipients is essential for optimizing organ allocation and estimating mortality outcomes. While models like the Model-for-End-Stage-Liver-Disease (MELD) predict 90-day mortality on the wait...
Computer methods and programs in biomedicine
39342876
BACKGROUND AND OBJECTIVE: In Pancreatic Ductal Adenocarcinoma (PDA), multi-omic models are emerging to answer unmet clinical needs to derive novel quantitative prognostic factors. We realized a pipeline that relies on survival machine-learning (SML) ...
BACKGROUND: Deep learning has made significant advancements in the field of digital pathology, and the integration of multiple models has further improved accuracy. In this study, we aimed to construct a combined prognostic model using deep learning-...
BACKGROUND: Whether machine learning approaches are superior to classical statistical models for survival analyses, especially in the case of lack of proportionality, is unknown.
Anoikis-related genes (ANRGs) are crucial in the invasion and metastasis of breast cancer (BC). The underlying role of ANRGs in the prognosis of breast cancer patients warrants further study. The anoikis-related prognostic signature (ANRS) was gene...
Computer methods and programs in biomedicine
39551025
BACKGROUND AND OBJECTIVES: The aim of this study is to develop a radiomic and deep learning-based signature for survival analysis of patients with Non-Small Cell Lung Cancer.
BACKGROUND: Despite decades of pursuing health equity, racial and ethnic disparities persist in healthcare in America. For cancer specifically, one of the leading observed disparities is worse mortality among non-Hispanic Black patients compared to n...
HIV remains a critical global health issue, with an estimated 39.9 million people living with the virus worldwide by the end of 2023 (according to WHO). Although the epidemic's impact varies significantly across regions, Africa remains the most affec...
An accelerated failure time (AFT) model assumes a log-linear relationship between failure times and a set of covariates. In contrast to other popular survival models that work on hazard functions, the effects of covariates are directly on failure tim...