AIMC Topic: Radiotherapy Dosage

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Dose evaluation of MRI-based synthetic CT generated using a machine learning method for prostate cancer radiotherapy.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists
Magnetic resonance imaging (MRI)-only radiotherapy treatment planning is attractive since MRI provides superior soft tissue contrast over computed tomographies (CTs), without the ionizing radiation exposure. However, it requires the generation of a s...

Prediction of skin dose in low-kV intraoperative radiotherapy using machine learning models trained on results of in vivo dosimetry.

Medical physics
PURPOSE: The purpose of this study was to implement a machine learning model to predict skin dose from targeted intraoperative (TARGIT) treatment resulting in timely adoption of strategies to limit excessive skin dose.

Predicting radiation pneumonitis in locally advanced stage II-III non-small cell lung cancer using machine learning.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Radiation pneumonitis (RP) is a radiotherapy dose-limiting toxicity for locally advanced non-small cell lung cancer (LA-NSCLC). Prior studies have proposed relevant dosimetric constraints to limit this toxicity. Using machine ...

Predictors of Nodal and Metastatic Failure in Early Stage Non-small-cell Lung Cancer After Stereotactic Body Radiation Therapy.

Clinical lung cancer
INTRODUCTION/BACKGROUND: Many patients with early stage non-small-cell lung cancer (ES-NSCLC) undergoing stereotactic body radiation therapy (SBRT) develop metastases, which is associated with poor outcomes. We sought to identify factors predictive o...

Automated data extraction and ensemble methods for predictive modeling of breast cancer outcomes after radiation therapy.

Medical physics
PURPOSE: The purpose of this study was to compare the effectiveness of ensemble methods (e.g., random forests) and single-model methods (e.g., logistic regression and decision trees) in predictive modeling of post-RT treatment failure and adverse eve...

Knowledge-based dose prediction models for head and neck cancer are strongly affected by interorgan dependency and dataset inconsistency.

Medical physics
PURPOSE: The goal of this study was to generate a large treatment plan database for head and neck (H&N) cancer patients that can be considered as the gold standard to train and validate models for knowledge-based (KB) treatment planning and QA. With ...

Deep-learning based surface region selection for deep inspiration breath hold (DIBH) monitoring in left breast cancer radiotherapy.

Physics in medicine and biology
Deep inspiration breath hold (DIBH) with surface supervising is a common technique for cardiac dose reduction in left breast cancer radiotherapy. Surface supervision accuracy relies on the characteristics of surface region. In this study, a convoluti...

DoseNet: a volumetric dose prediction algorithm using 3D fully-convolutional neural networks.

Physics in medicine and biology
The goal of this study is to demonstrate the feasibility of a novel fully-convolutional volumetric dose prediction neural network (DoseNet) and test its performance on a cohort of prostate stereotactic body radiotherapy (SBRT) patients. DoseNet is su...

Automatic treatment planning based on three-dimensional dose distribution predicted from deep learning technique.

Medical physics
PURPOSE: To develop an automated treatment planning strategy for external beam intensity-modulated radiation therapy (IMRT), including a deep learning-based three-dimensional (3D) dose prediction and a dose distribution-based plan generation algorith...