AIMC Topic: Rats, Sprague-Dawley
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Influences of Edaravone on Necroptosis-Related Proteins and Oxidative Stress in Rats with Lower Extremity Ischemia/Reperfusion Injury.
Cellular and molecular biology (Noisy-le-Grand, France)
Jul 31, 2022
The study aimed to investigate the influences of edaravone on necroptosis-related proteins and oxidative stress in rats with lower extremity ischemia/reperfusion (I/R) injury. The normal group (n=10), model group (lower extremity I/R injury model, n=...
Production of Bioactive Substances to Alleviates Hangover and Ethanol-Induced Liver Damage through Fermentation of Using .
Molecules (Basel, Switzerland)
Feb 9, 2022
The purpose of this study is to evaluate the effect of the bioconversion products of extract fermented by (OEFL) on relieving hangovers and improving liver function. In addition, the bioactive substance of the OEFL, which alleviates hangover and et...
Quantitative Assessment of Epithelial Proliferation in Rat Mammary Gland Using Artificial Intelligence Independent of Choice of Proliferation Marker.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Jan 20, 2022
Epithelial proliferation in the rat mammary gland is recommended in regulatory guidelines as an endpoint for assessment of the in vivo carcinogenic potential of insulin analogues. Epithelial proliferation is traditionally assessed by immunohistochemi...
The Anti-Adiposity Mechanisms of Ampelopsin and Vine Tea Extract in High Fat Diet and Alcohol-Induced Fatty Liver Mouse Models.
Molecules (Basel, Switzerland)
Jan 18, 2022
(AG) is an ancient medicinal plant that is mainly distributed and used in southwest China. It exerts therapeutic effects, such as antioxidant, anti-diabetic, and anti-inflammatory activities, reductions in blood pressure and cholesterol and hepatopr...
Implementation and Practice of Deep Learning-Based Instance Segmentation Algorithm for Quantification of Hepatic Fibrosis at Whole Slide Level in Sprague-Dawley Rats.
Toxicologic pathology
Dec 5, 2021
Exponential development in artificial intelligence or deep learning technology has resulted in more trials to systematically determine the pathological diagnoses using whole slide images (WSIs) in clinical and nonclinical studies. In this study, we a...
Ultrasound deep learning for monitoring of flow-vessel dynamics in murine carotid artery.
Ultrasonics
Nov 9, 2021
Several arterial diseases are closely related with mechanical properties of the blood vessel and interactions of flow-vessel dynamics such as mean flow velocity, wall shear stress (WSS) and vascular strain. However, there is an opportunity to improve...
Prioritization of Mycotoxins Based on Their Genotoxic Potential with an In Silico-In Vitro Strategy.
Toxins
Oct 19, 2021
Humans are widely exposed to a great variety of mycotoxins and their mixtures. Therefore, it is important to design strategies that allow prioritizing mycotoxins based on their toxic potential in a time and cost-effective manner. A strategy combining...
Ferromagnetic soft catheter robots for minimally invasive bioprinting.
Nature communications
Aug 20, 2021
In vivo bioprinting has recently emerged as a direct fabrication technique to create artificial tissues and medical devices on target sites within the body, enabling advanced clinical strategies. However, existing in vivo bioprinting methods are ofte...
Two-step machine learning method for the rapid analysis of microvascular flow in intravital video microscopy.
Scientific reports
May 11, 2021
Microvascular blood flow is crucial for tissue and organ function and is often severely affected by diseases. Therefore, investigating the microvasculature under different pathological circumstances is essential to understand the role of the microcir...
DeepACSON automated segmentation of white matter in 3D electron microscopy.
Communications biology
Feb 10, 2021
Tracing the entirety of ultrastructures in large three-dimensional electron microscopy (3D-EM) images of the brain tissue requires automated segmentation techniques. Current segmentation techniques use deep convolutional neural networks (DCNNs) and r...
Artificial Intelligence
Reproducibility of Results
Mitochondria
Image Interpretation, Computer-Assisted
White Matter
Brain Injuries, Traumatic
Cell Nucleus
Nerve Fibers, Myelinated
Rats, Sprague-Dawley
Microscopy, Electron
Disease Models, Animal
Animals
Predictive Value of Tests
Male
Imaging, Three-Dimensional
Rats
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