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Rats, Wistar

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A non-linear mathematical model using optical sensor to predict heart decellularization efficacy.

Scientific reports
One of the main problems of the decellularization technique is the subjectivity of the final evaluation of its efficacy in individual organs. This problem can result in restricted cell repopulation reproducibility and worse responses to transplant ti...

Comparison between two programs for image analysis, machine learning and subsequent classification.

Tissue & cell
In the early 1950s, flow cytometry was developed as the first method for automated quantitative cellular analysis. In the early 1990s, the first equipment for image cytometry (laser scanning cytometry, LSC) became commercially available. As flow cyto...

Metabolomics predicts the pharmacological profile of new psychoactive substances.

Journal of psychopharmacology (Oxford, England)
BACKGROUND: The unprecedented proliferation of new psychoactive substances (NPS) threatens public health and challenges drug policy. Information on NPS pharmacology and toxicity is, in most cases, unavailable or very limited and, given the large numb...

Afferent Input Induced by Rhythmic Limb Movement Modulates Spinal Neuronal Circuits in an Innovative Robotic In Vitro Preparation.

Neuroscience
Locomotor patterns are mainly modulated by afferent feedback, but its actual contribution to spinal network activity during continuous passive limb training is still unexplored. To unveil this issue, we devised a robotic in vitro setup (Bipedal Induc...

[Experimental study of a new animal model with trigeminal neuralgia produced by administration of talc to peripheral infraobital nerve in rats].

Shanghai kou qiang yi xue = Shanghai journal of stomatology
PURPOSE: To establish a new animal model of trigeminal neuralgia(TN) produced by administration of talc to peripheral infraobital nerve in rats.

Implementation of deep neural networks to count dopamine neurons in substantia nigra.

The European journal of neuroscience
Unbiased estimates of neuron numbers within substantia nigra are crucial for experimental Parkinson's disease models and gene-function studies. Unbiased stereological counting techniques with optical fractionation are successfully implemented, but ar...

A Histological Study of Vasoconstriction by Local Anesthetics in Mandible.

Anesthesia progress
To assess the effect of epinephrine-containing local anesthetics on vasoconstriction, we immunohistochemically measured the intravascular lumen area in different regions of the mandible. Twelve male Wistar rats were used. General anesthesia was induc...

Change in hippocampal theta oscillation associated with multiple lever presses in a bimanual two-lever choice task for robot control in rats.

PloS one
Hippocampal theta oscillations have been implicated in working memory and attentional process, which might be useful for the brain-machine interface (BMI). To further elucidate the properties of the hippocampal theta oscillations that can be used in ...

The role of neuron-glia interactions in the emergence of ultra-slow oscillations.

Biological cybernetics
Ultra-slow cortical oscillatory activity of 1-100 mHz has been recorded in human by electroencephalography and in dissociated cultures of cortical rat neurons, but the underlying mechanisms remain to be elucidated. This study presents a computational...