AIMC Topic: RAW 264.7 Cells

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Noninvasive detection of macrophage activation with single-cell resolution through machine learning.

Proceedings of the National Academy of Sciences of the United States of America Mar 6, 2018
We present a method enabling the noninvasive study of minute cellular changes in response to stimuli, based on the acquisition of multiple parameters through label-free microscopy. The retrieved parameters are related to different attributes of the c...
Machine Learning Animals Single-Cell Analysis Dose-Response Relationship, Drug Microscopy, Fluorescence Models, Biological RAW 264.7 Cells Macrophage Activation Progesterone Image Processing, Computer-Assisted Spectrum Analysis, Raman Mice Lipopolysaccharides
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Gastro-protective effect of edible plant Artemisia argyi in ethanol-induced rats via normalizing inflammatory responses and oxidative stress.

Journal of ethnopharmacology Dec 20, 2017
PHARMACOLOGICAL RELEVANCE: Artemisia argyi, a kind of ethnic drug, has a long-term use on gastric diseases and syndromes.
Inflammation Mediators RAW 264.7 Cells Macrophages Free Radicals Animals Cytoprotection Rats, Wistar Oxidative Stress Phytotherapy Mice Malondialdehyde Anti-Inflammatory Agents Ethanol Antioxidants Anti-Ulcer Agents Stomach Ulcer Superoxide Dismutase Disease Models, Animal Artemisia Plant Extracts Gastric Mucosa Plants, Medicinal
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Elevation of serum pyruvate kinase M2 (PKM2) in IBD and its relationship to IBD indices.

Clinical biochemistry Dec 19, 2017
OBJECTIVES: Endoscopy remains the gold standard to diagnose and evaluate inflammatory bowel disease (IBD) activity. Current biomarkers or their combinations cannot adequately predict IBD risk, diagnosis, progression or relapse, and response to therap...
Caco-2 Cells RAW 264.7 Cells Pyruvate Kinase Gastrointestinal Microbiome Dysbiosis Inflammatory Bowel Diseases Female Adult Animals Male Mice Humans Biomarkers
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Inhibitory activity of linarin on osteoclastogenesis through receptor activator of nuclear factor κB ligand-induced NF-κB pathway.

Biochemical and biophysical research communications Dec 18, 2017
Linarin, a natural flavonoid glycoside widely found in plants, has been reported to possess anti-inflammation, neuroprotection and osteogenic properties. However, its impact on osteoclast remains unclear. In the present study, the effects of linarin ...
Dose-Response Relationship, Drug NF-kappa B Osteogenesis RANK Ligand Mice, Inbred C57BL RAW 264.7 Cells Osteoblasts Glycosides Cells, Cultured Macrophages Animals Mice Signal Transduction
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Exploration of Active Substances and Its Potential Mechanism of Gancao Fuzi Decoction on Inflammatory Based on Metabolomics and Network Pharmacology.

Rapid communications in mass spectrometry : RCM May 30, 2025
Gancao Fuzi decoction (GCFZT) is a traditional Chinese formula, which has been commonly used in clinical practice to treat inflammatory diseases. However, the active substance of GCFZT in the treatment of inflammation is not fully clarified. In this ...
Signal Transduction Metabolomics Drugs, Chinese Herbal Mice Inflammation Tandem Mass Spectrometry RAW 264.7 Cells Network Pharmacology NF-kappa B Anti-Inflammatory Agents Chromatography, High Pressure Liquid Animals
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Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation.

Pharmaceutical biology Dec 1, 2018
CONTEXT: Ajuga ovalifolia Bur. et Franch. var. calantha (Diels) C. Y. Wu et C. Chen (Labiatae), a traditional Chinese medicine, has been used to treat several inflammatory diseases.
RAW 264.7 Cells Ajuga Lipopolysaccharides Inflammation Male Macrophages Disease Models, Animal Dose-Response Relationship, Drug Mice Animals Anti-Inflammatory Agents Plant Extracts
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