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Reactive Oxygen Species

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Antibacterial mechanisms of a novel type picosecond laser-generated silver-titanium nanoparticles and their toxicity to human cells.

International journal of nanomedicine
In this study, we explored the antibacterial mechanisms for a novel type of Ag-TiO compound nanoparticles (NPs) produced from an Ag-TiO alloy using a picosecond laser and evaluated the toxicity of the Ag-TiO NPs to a range of human cell types. Transm...

Biosynthesis of copper nanoparticles using Shewanella loihica PV-4 with antibacterial activity: Novel approach and mechanisms investigation.

Journal of hazardous materials
Metallic nanoparticle based disinfection represents a promising approach for microbial pollution control in drinking water and thus, biosynthesis of non precious metal nanoparticles is of considerable interest. Herein, an original and efficient route...

Nitric oxide-releasing injectable hydrogels with high antibacterial activity through in situ formation of peroxynitrite.

Acta biomaterialia
UNLABELLED: Nitric oxide (NO) is an endogenous molecule with many critical biological functions that depend on its concentration. At high levels, NO provides broad-spectrum antibacterial effects through both its pathogen inhibition and killing abilit...

Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and inflammation damage.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Ginsenoside Rg1, one of the most notable active components of Panax ginseng, has been widely reported to exert anti-inflammatory actions. This study aimed to reveal whether ginsenoside Rg1 also exhibits beneficial roles against lipopolysaccharide (LP...

Transcriptomic alterations in Sitophilus zeamais in response to allyl isothiocyanate fumigation.

Pesticide biochemistry and physiology
To study the fumigation mechanisms of Allyl isothiocyanate (AITC) a promising biorational alternative to present fumigants (phosphine and methyl bromide), and provide theoretical basis for its further development in the control of stored grain pests,...

Dysfunction of endothelial progenitor cells in hyperlipidemic rats involves the increase of NADPH oxidase derived reactive oxygen species production.

Canadian journal of physiology and pharmacology
NADPH oxidase (NOX) is a major source of reactive oxygen species (ROS) in the body and it plays a key role in mediation of oxidative injury in the cardiovascular system. The purposes of this study are to evaluate the status of NOX in endothelial prog...

Anethole improves the in vitro development of isolated caprine secondary follicles.

Theriogenology
The aim of this study was to investigate the effect of three concentrations of anethole (30, 300, and 2000 μg/mL) on survival, antrum formation, follicular diameter, and oocyte maturation in the caprine species. The study also evaluated the effects o...

[Oxidative stress and mitochondrion-related cell apoptosis in human bronchial epithelial 16HBE cells induced by silica dust].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases
OBJECTIVE: To investigate oxidative stress and mitochondria-related cell apoptosis induced by silica dust in human normal bronchial epithelial 16HBE cells.

Preparation, characterization and toxicological investigation of copper loaded chitosan nanoparticles in human embryonic kidney HEK-293 cells.

Materials science & engineering. C, Materials for biological applications
Metallic nanoparticles often attribute severe adverse effects to the various organs or tissues at the molecular level despite of their applications in medical, laboratory and industrial sectors. The present study highlights the preparation of copper ...