AIMC Topic: Regenerative Medicine

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Biological Robots: Perspectives on an Emerging Interdisciplinary Field.

Soft robotics
Advances in science and engineering often reveal the limitations of classical approaches initially used to understand, predict, and control phenomena. With progress, conceptual categories must often be re-evaluated to better track recently discovered...

Predicting multipotency of human adult stem cells derived from various donors through deep learning.

Scientific reports
Adult stem cell-based therapeutic approaches have great potential in regenerative medicine because of their immunoregulatory properties and multidifferentiation capacity. Nevertheless, the outcomes of stem cell‑based therapies to date have shown inco...

Implementing robotics and artificial intelligence.

eLife
An automated platform for cell culture combines robotics and artificial intelligence to optimize cell culture protocols and reliably produce specific cell types that could be used for regenerative medicine treatments.

The future of bone regeneration: integrating AI into tissue engineering.

Biomedical physics & engineering express
Tissue engineering is a branch of regenerative medicine that harnesses biomaterial and stem cell research to utilise the body's natural healing responses to regenerate tissue and organs. There remain many unanswered questions in tissue engineering, w...

Potential applications of deep learning in single-cell RNA sequencing analysis for cell therapy and regenerative medicine.

Stem cells (Dayton, Ohio)
When used in cell therapy and regenerative medicine strategies, stem cells have potential to treat many previously incurable diseases. However, current application methods using stem cells are underdeveloped, as these cells are used directly regardle...

Identification of an epigenetic signature in human induced pluripotent stem cells using a linear machine learning model.

Human cell
The use of human induced pluripotent stem cells (iPSCs), used as an alternative to human embryonic stem cells (ESCs), is a potential solution to challenges, such as immune rejection, and does not involve the ethical issues concerning the use of ESCs ...

Machine learning uncovers cell identity regulator by histone code.

Nature communications
Conversion between cell types, e.g., by induced expression of master transcription factors, holds great promise for cellular therapy. Our ability to manipulate cell identity is constrained by incomplete information on cell identity genes (CIGs) and t...

Improving patient outcomes with regenerative medicine: How the Regenerative Medicine Manufacturing Society plans to move the needle forward in cell manufacturing, standards, 3D bioprinting, artificial intelligence-enabled automation, education, and training.

Stem cells translational medicine
The Regenerative Medicine Manufacturing Society (RMMS) is the first and only professional society dedicated toward advancing manufacturing solutions for the field of regenerative medicine. RMMS's vision is to provide greater patient access to regener...

Improving the Rate of Translation of Tissue Engineering Products.

Advanced healthcare materials
Over 100 000 research articles and 9000 patents have been published on tissue engineering (TE) in the past 20 years. Yet, very few TE products have made their way to the market during the same period. Experts have proposed a variety of strategies to ...