AI Medical Compendium Topic

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Unsupervised Clustering of Missense Variants in HNF1A Using Multidimensional Functional Data Aids Clinical Interpretation.

American journal of human genetics
Exome sequencing in diabetes presents a diagnostic challenge because depending on frequency, functional impact, and genomic and environmental contexts, HNF1A variants can cause maturity-onset diabetes of the young (MODY), increase type 2 diabetes ris...

Improving preoperative risk-of-death prediction in surgery congenital heart defects using artificial intelligence model: A pilot study.

PloS one
BACKGROUND: Congenital heart disease accounts for almost a third of all major congenital anomalies. Congenital heart defects have a significant impact on morbidity, mortality and health costs for children and adults. Research regarding the risk of pr...

Machine Learning Prediction of Stroke Mechanism in Embolic Strokes of Undetermined Source.

Stroke
BACKGROUND AND PURPOSE: One-fifth of ischemic strokes are embolic strokes of undetermined source (ESUS). Their theoretical causes can be classified as cardioembolic versus noncardioembolic. This distinction has important implications, but the categor...

Prediction of 1-Year Mortality from Acute Myocardial Infarction Using Machine Learning.

The American journal of cardiology
Risk stratification at hospital discharge could be instrumental in guiding postdischarge care. In this study, the risk models for 1-year mortality using machine learning (ML) were evaluated for guiding management of acute myocardial infarction (AMI) ...

Identification of Patients with Heart Failure in Large Datasets.

Heart failure clinics
Large registries, administrative data, and the electronic health record (EHR) offer opportunities to identify patients with heart failure, which can be used for research purposes, process improvement, and optimal care delivery. Identification of case...

Defining heterogeneity of epicardial functional stenosis with low coronary flow reserve by unsupervised machine learning.

Heart and vessels
Low CFR is associated with poor prognosis, whereas it is a heterogeneous condition according to the actual coronary flow, such as high resting or low hyperemic coronary flow, which should have different physiological traits and clinical implications....

Prediction of in-hospital mortality in patients with post traumatic brain injury using National Trauma Registry and Machine Learning Approach.

Scandinavian journal of trauma, resuscitation and emergency medicine
BACKGROUND: The use of machine learning techniques to predict diseases outcomes has grown significantly in the last decade. Several studies prove that the machine learning predictive techniques outperform the classical multivariate techniques. We aim...