AIMC Topic: Retrospective Studies

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A machine learning-based predictive model for multilobar pulmonary consolidation induced by macrolide-resistant pneumonia caused by the 23S rRNA A2063G mutation.

Microbiology spectrum
This study aims to develop a machine learning (ML)-based predictive model for assessing the risk of multilobar pulmonary consolidation in children with macrolide-resistant pneumonia (MRMP) caused by the 23S rRNA A2063G mutation, a subgroup underrepr...

Developing an explainable machine learning model to predict false-negative citrin deficiency cases in newborn screening.

Orphanet journal of rare diseases
BACKGROUND: Neonatal Intrahepatic Cholestasis caused by Citrin Deficiency (NICCD) is an autosomal recessive disorder affecting the urea cycle and energy metabolism. Newborn screening (NBS) usually relies on elevated citrulline, but some patients have...

Machine learning reveals limited predictive value of clinical factors for asthma exacerbations.

Scientific reports
While predictors of asthma exacerbation risk are generally well established, predictors of exacerbation severity remain largely undefined. Identifying robust clinical predictors of exacerbation severity is essential to support tailored management str...

Virtual contrast-enhanced maximum intensity projections from high-b-value diffusion-weighted breast MRI: a feasibility study.

European radiology experimental
BACKGROUND: Maximum intensity projections (MIPs) facilitate rapid lesion detection both for contrast-enhanced (CE) and diffusion-weighted imaging (DWI) breast magnetic resonance imaging (MRI). We evaluated the feasibility of AI-based virtual CE subtr...

Machine learning-based prediction of N2 lymph node metastasis in non-small cell lung cancer.

BMC pulmonary medicine
BACKGROUND: Lung cancer is a leading cause of cancer-related mortality worldwide. Accurate staging of mediastinal lymph nodes is a crucial step in determining appropriate treatment approaches. Current noninvasive diagnostic methods do not provide suf...

The diagnostic value of serum cysteine protease inhibitor (CST4) in colorectal cancer: a preliminary study.

BMC gastroenterology
BACKGROUND: CST4 is associated with various cancers but its diagnostic value in colorectal cancer (CRC) has not been clearly established. This study aims to further validate the diagnostic value of CST4 in colorectal cancer using random forest models...

Support vector machine-based preoperative identification of IDH-Mutant low-grade gliomas in adult gliomas using clinical features.

BMC neurology
BACKGROUND: The preoperative identification of (isocitrate dehydrogenase) IDH-mutant low-grade gliomas (LGGs) is critical for personalized treatment planning. We aimed to develop a streamlined machine-learning model using key clinical features for ra...

Predicting hematologic toxicity in advanced cervical cancer patients using interpretable machine learning models based on radiomics and dosimetrics.

BMC cancer
BACKGROUND AND OBJECTIVES: Hematologic toxicity (HT) is a common and serious side effect for advanced cervical cancer patients undergoing chemoradiotherapy. Accurately predicting HT can significantly improve patient management and treatment outcomes....