BACKGROUND: Postoperative recurrence risk for pediatric low-grade gliomas (pLGGs) is challenging to predict by conventional clinical, radiographic, and genomic factors. We investigated if deep learning (DL) of magnetic resonance imaging (MRI) tumor f...
Investigative ophthalmology & visual science
Jan 2, 2025
PURPOSE: Descemet membrane endothelial keratoplasty (DMEK) has emerged as a novel approach in corneal transplantation over the past two decades. This study aims to identify predisposing risk factors for post-DMEK ocular hypertension (OHT) and develop...
Translational vision science & technology
Jan 2, 2025
PURPOSE: The purpose of this study was to develop a deep learning approach that restores artifact-laden optical coherence tomography (OCT) scans and predicts functional loss on the 24-2 Humphrey Visual Field (HVF) test.
Preeclampsia is a pregnancy-specific disease characterized by new onset hypertension after 20 weeks of gestation that affects 2-8% of all pregnancies and contributes to up to 26% of maternal deaths. Despite extensive clinical research, current predic...
This study aimed to compare image quality and solid focal liver lesion (FLL) assessments between free-breathing, diffusion-weighted imaging using deep learning reconstruction (FB-DL-DWI) and conventional DWI (FB-C-DWI) in patients undergoing clinical...
OBJECTIVE: The objective of this study is to compare the clinical features and survival outcomes of class IV ± V lupus nephritis (LN) patients, identify risk factors, and develop an accurate prognostic model.
OBJECTIVE: To develop and validate an interpretable machine learning (ML) model for the preoperative prediction of central lymph node metastasis (CLNM) in papillary thyroid microcarcinoma (PTMC).
BACKGROUND: Childhood obesity poses a significant risk to bone health, but the impact of insulin resistance (IR) on bone metabolism in prepubertal children, as assessed by the triglyceride-glucose (TyG) index, remains underexplored. Bone turnover mar...
PURPOSE: Voriconazole (VCZ) is a first-line treatment for invasive fungal disease, characterized by a narrow therapeutic window and significant inter-individual variability. It is primarily metabolized by the liver, the function of which declines wit...
Parkinson's disease (PD) is an increasingly prevalent neurologic condition for which symptomatic, but not preventative, treatment is available. Drug repurposing is an innovate drug discovery method that uncovers existing therapeutics to treat or prev...
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