AIMC Topic: Risk Assessment

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LASSO-Based Machine Learning Algorithm for Prediction of Lymph Node Metastasis in T1 Colorectal Cancer.

Cancer research and treatment
PURPOSE: The role of tumor-infiltrating lymphocytes (TILs) in predicting lymph node metastasis (LNM) in patients with T1 colorectal cancer (CRC) remains unclear. Furthermore, clinical utility of a machine learning-based approach has not been widely s...

Characterization of Antiphospholipid Syndrome Atherothrombotic Risk by Unsupervised Integrated Transcriptomic Analyses.

Arteriosclerosis, thrombosis, and vascular biology
OBJECTIVE: Our aim was to characterize distinctive clinical antiphospholipid syndrome phenotypes and identify novel microRNA (miRNA)-mRNA-intracellular signaling regulatory networks in monocytes linked to cardiovascular disease. Approach and Results:...

Use of Machine Learning to Develop a Risk-Stratification Tool for Emergency Department Patients With Acute Heart Failure.

Annals of emergency medicine
STUDY OBJECTIVE: We use variables from a recently derived acute heart failure risk-stratification rule (STRATIFY) as a basis to develop and optimize risk prediction using additional patient clinical data from electronic health records and machine-lea...

Validation of the Al-based Predictive OpTimal Trees in Emergency Surgery Risk (POTTER) Calculator in Patients 65 Years and Older.

Annals of surgery
OBJECTIVE: We sought to assess the performance of the Predictive OpTimal Trees in Emergency Surgery Risk (POTTER) tool in elderly emergency surgery (ES) patients.

Assessing Drug Development Risk Using Big Data and Machine Learning.

Cancer research
Identifying new drug targets and developing safe and effective drugs is both challenging and risky. Furthermore, characterizing drug development risk, the probability that a drug will eventually receive regulatory approval, has been notoriously hard ...

Predicting the Development of Surgery-Related Pressure Injury Using a Machine Learning Algorithm Model.

The journal of nursing research : JNR
BACKGROUND: Surgery-related pressure injury (SRPI) is a serious problem in patients who undergo cardiovascular surgery. Identifying patients at a high risk of SRPI is important for clinicians to recognize and prevent it expeditiously. Machine learnin...

A deep learning backcasting approach to the electrolyte, metabolite, and acid-base parameters that predict risk in ICU patients.

PloS one
BACKGROUND: A powerful risk model allows clinicians, at the bedside, to ensure the early identification of and decision-making for patients showing signs of developing physiological instability during treatment. The aim of this study was to enhance t...

Continuous and automatic mortality risk prediction using vital signs in the intensive care unit: a hybrid neural network approach.

Scientific reports
Mortality risk prediction can greatly improve the utilization of resources in intensive care units (ICUs). Existing schemes in ICUs today require laborious manual input of many complex parameters. In this work, we present a scheme that uses variation...