AIMC Topic: Saponins

Clear Filters Showing 11 to 18 of 18 articles

Achyranthes bidentate saponins protect rat articular chondrocytes against interleukin-1β-induced inflammation and apoptosis in vitro.

The Kaohsiung journal of medical sciences Dec 30, 2016
Achyranthes bidentate Blume (Niuxi) is often employed for treatment of arthritis in Traditional Chinese Medicine and possesses anti-inflammatory properties. Phytochemical and pharmacological studies proved the oleanane-type saponins to be the main bi...
bcl-X Protein Plant Roots Plant Extracts Interleukin-1beta Rats NF-kappa B Inflammation Matrix Metalloproteinase 9 Animals bcl-2-Associated X Protein Male Apoptosis Signal Transduction Caspase 3 Rats, Sprague-Dawley Anti-Inflammatory Agents, Non-Steroidal Primary Cell Culture Tumor Suppressor Protein p53 Achyranthes Chondrocytes Cyclooxygenase 2 Gene Expression Regulation bcl-Associated Death Protein Saponins Cartilage, Articular Proliferating Cell Nuclear Antigen Matrix Metalloproteinase 3
View on PubMed DOI

Antifungal activity of sterols and dipsacus saponins isolated from Dipsacus asper roots against phytopathogenic fungi.

Pesticide biochemistry and physiology Dec 18, 2016
The in vivo antifungal activity of crude extracts of Dipsacus asper roots was evaluated against the phytopathogenic fungi Botrytis cinerea, Colletotrichum coccodes, Blumeria graminis f. sp. hordei, Magnaporthe grisea, Phytophthora infestans, Puccinia...
Oleanolic Acid Cholesterol Dipsacaceae Plant Roots Saponins Antifungal Agents Phytosterols Sitosterols Sterols
View on PubMed DOI

Simultaneous Determination of Five Active Components in the Chinese Patent Medicine Niuhuang Jiangya Pill by HPLC-MS/MS.

Journal of AOAC International Dec 16, 2016
Niuhuang Jiangya (NHJY) pill is one of the well-known Chinese patent medicines in China used in the treatment of high blood pressure. The primary purpose of this study was to establish and validate a method using HPLC with tandem MS for the quality e...
Coumaric Acids Emodin Monoterpenes Triterpenes Glucosides Chromatography, High Pressure Liquid Tandem Mass Spectrometry Saponins Biological Products China Flavonoids Drugs, Chinese Herbal
View on PubMed DOI

A simple and sensitive UHPLC-MS/MS method for quantification of buddlejasaponin IV in rat plasma and its application to a pharmacokinetic study.

Journal of pharmaceutical and biomedical analysis Dec 29, 2015
Buddlejasaponin IV (BS-IV), a natural triterpene saponin isolated from several herbal plants, has drawn a lot of attention for its anti-inflammatory, antinociceptive, antihyperlipidemia, and antitumor activities. In this study, a simple and sensitive...
Tandem Mass Spectrometry Male Administration, Oral Rats, Wistar Saponins Dose-Response Relationship, Drug Animals Rats Triterpenes Chromatography, High Pressure Liquid
View on PubMed DOI

[Safety and Tolerance of Healthy People to Injection of Astragalosides-a New Drug for Coronary Heart Disease].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition Sep 1, 2016
OBJECTIVES: To assess the safety and tolerance of healthy volunteers to as tragalosides injection (AGI), and to determine a safe dose range for phase II clinical trial.
Triterpenes Humans Healthy Volunteers Liver Coronary Disease Saponins Drugs, Chinese Herbal
View on PubMed

[Optimization of Formulation of Panax notoginseng Saponins Transfersomes].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials Dec 1, 2015
OBJECTIVE: To optimize the formulation of Panax notoginseng saponins (PNS) transfersomes.
Drugs, Chinese Herbal Plants, Medicinal Panax notoginseng Saponins Chemistry, Pharmaceutical Ginsenosides
View on PubMed

[HPLC simultaneous determination of contents of 5 saponin constituents in Ophiopogonis Radix].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica Oct 1, 2015
This research is to establish an HPLC method for the simultaneous determination of ophiopogonin D, ophiopogonin D', ophiopogonin C, deacetylophiopojaponin A and ophiogenin-3-O-α-L-rhamnosyl-(1-->2)-β-D-glucoside in Ophiopogonis Radix. HPLC-ELSD analy...
Plant Roots Drugs, Chinese Herbal Ophiopogon Chromatography, High Pressure Liquid Saponins
View on PubMed

[Protective Effects of Total Saponins from Panax japonicus on H₂O₂Induced Injury via Mitochondia Pathway in SH-SY5Y Cells].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials Aug 1, 2015
OBJECTIVE: To investigate the protective mechanism of total saponins from Panax japonicus (SPJ) on H₂O₂ induced injury in SH-SY5Y cells.
Panax Oxidative Stress Cell Line Membrane Potential, Mitochondrial Mitochondria Saponins Humans Hydrogen Peroxide
View on PubMed
Popular Topics
Recent Journals