AIMC Topic: Software

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Sensitivity analysis for interpretation of machine learning based segmentation models in cardiac MRI.

BMC medical imaging
BACKGROUND: Image segmentation is a common task in medical imaging e.g., for volumetry analysis in cardiac MRI. Artificial neural networks are used to automate this task with performance similar to manual operators. However, this performance is only ...

DeepCAPE: A Deep Convolutional Neural Network for the Accurate Prediction of Enhancers.

Genomics, proteomics & bioinformatics
The establishment of a landscape of enhancers across human cells is crucial to deciphering the mechanism of gene regulation, cell differentiation, and disease development. High-throughput experimental approaches, which contain successfully reported e...

Towards effective deep transfer via attentive feature alignment.

Neural networks : the official journal of the International Neural Network Society
Training a deep convolutional network from scratch requires a large amount of labeled data, which however may not be available for many practical tasks. To alleviate the data burden, a practical approach is to adapt a pre-trained model learned on the...

Radiomic Machine Learning Classifiers in Spine Bone Tumors: A Multi-Software, Multi-Scanner Study.

European journal of radiology
PURPOSE: Spinal lesion differential diagnosis remains challenging even in MRI. Radiomics and machine learning (ML) have proven useful even in absence of a standardized data mining pipeline. We aimed to assess ML diagnostic performance in spinal lesio...

Automatic deep learning-driven label-free image-guided patch clamp system.

Nature communications
Patch clamp recording of neurons is a labor-intensive and time-consuming procedure. Here, we demonstrate a tool that fully automatically performs electrophysiological recordings in label-free tissue slices. The automation covers the detection of cell...

New machine learning and physics-based scoring functions for drug discovery.

Scientific reports
Scoring functions are essential for modern in silico drug discovery. However, the accurate prediction of binding affinity by scoring functions remains a challenging task. The performance of scoring functions is very heterogeneous across different tar...

Deep Coattention-Based Comparator for Relative Representation Learning in Person Re-Identification.

IEEE transactions on neural networks and learning systems
Person re-identification (re-ID) favors discriminative representations over unseen shots to recognize identities in disjoint camera views. Effective methods are developed via pair-wise similarity learning to detect a fixed set of region features, whi...

Use of a Commercially Available Deep Learning Algorithm to Measure the Solid Portions of Lung Cancer Manifesting as Subsolid Lesions at CT: Comparisons with Radiologists and Invasive Component Size at Pathologic Examination.

Radiology
Background The solid portion size of lung cancer lesions manifesting as subsolid lesions is key in their management, but the automatic measurement of such lesions by means of a deep learning (DL) algorithm needs evaluation. Purpose To evaluate the pe...

Computational identification of ubiquitination sites in Arabidopsis thaliana using convolutional neural networks.

Plant molecular biology
We developed two CNNs for predicting ubiquitination sites in Arabidopsis thaliana, demonstrated their competitive performance, analyzed amino acid physicochemical properties and the CNN structures, and predicted ubiquitination sites in Arabidopsis. A...

Machine learning transition temperatures from 2D structure.

Journal of molecular graphics & modelling
A priori knowledge of physicochemical properties such as melting and boiling could expedite materials discovery. However, theoretical modeling from first principles poses a challenge for efficient virtual screening of potential candidates. As an alte...