AIMC Topic:
Software

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Cross-species regulatory sequence activity prediction.

PLoS computational biology
Machine learning algorithms trained to predict the regulatory activity of nucleic acid sequences have revealed principles of gene regulation and guided genetic variation analysis. While the human genome has been extensively annotated and studied, mod...

A novel riboswitch classification based on imbalanced sequences achieved by machine learning.

PLoS computational biology
Riboswitch, a part of regulatory mRNA (50-250nt in length), has two main classes: aptamer and expression platform. One of the main challenges raised during the classification of riboswitch is imbalanced data. That is a circumstance in which the recor...

Designing a Cyber-Physical System for Ambient Assisted Living: A Use-Case Analysis for Social Robot Navigation in Caregiving Centers.

Sensors (Basel, Switzerland)
The advances of the Internet of Things, robotics, and Artificial Intelligence, to give just a few examples, allow us to imagine promising results in the development of smart buildings in the near future. In the particular case of elderly care, there ...

Automatic CT image segmentation of maxillary sinus based on VGG network and improved V-Net.

International journal of computer assisted radiology and surgery
PURPOSE: The analysis of the maxillary sinus (MS) can provide an assessment for many clinical diagnoses, so accurate CT image segmentation of the MS is essential. However, common segmentation methods are mainly done by experienced doctors manually, a...

Manual segmentation versus semi-automated segmentation for quantifying vestibular schwannoma volume on MRI.

International journal of computer assisted radiology and surgery
PURPOSE: Management of vestibular schwannoma (VS) is based on tumour size as observed on T1 MRI scans with contrast agent injection. The current clinical practice is to measure the diameter of the tumour in its largest dimension. It has been shown th...

Exploiting defective RRAM array as synapses of HTM spatial pooler with boost-factor adjustment scheme for defect-tolerant neuromorphic systems.

Scientific reports
A crossbar array architecture employing resistive switching memory (RRAM) as a synaptic element accelerates vector-matrix multiplication in a parallel fashion, enabling energy-efficient pattern recognition. To implement the function of the synapse in...

Structural compliance: A new metric for protein flexibility.

Proteins
Proteins are the active players in performing essential molecular activities throughout biology, and their dynamics has been broadly demonstrated to relate to their mechanisms. The intrinsic fluctuations have often been used to represent their dynami...

Automated detection and quantification of COVID-19 pneumonia: CT imaging analysis by a deep learning-based software.

European journal of nuclear medicine and molecular imaging
BACKGROUND: The novel coronavirus disease 2019 (COVID-19) is an emerging worldwide threat to public health. While chest computed tomography (CT) plays an indispensable role in its diagnosis, the quantification and localization of lesions cannot be ac...

Deep-learning-based accurate hepatic steatosis quantification for histological assessment of liver biopsies.

Laboratory investigation; a journal of technical methods and pathology
Hepatic steatosis droplet quantification with histology biopsies has high clinical significance for risk stratification and management of patients with fatty liver diseases and in the decision to use donor livers for transplantation. However, patholo...