IMPORTANCE: Electronic health records (EHRs) provide a low-cost means of accessing detailed longitudinal clinical data for large populations. A lung cancer cohort assembled from EHR data would be a powerful platform for clinical outcome studies.
BACKGROUD: Cancer stemness is associated with metastases in kidney renal clear cell carcinoma (KIRC) and negatively correlates with immune infiltrates. Recent stemness evaluation methods based on the absolute expression have been proposed to reveal t...
OBJECTIVE: This study evaluates the ability of several machine learning (ML) algorithms, developed using volumetric and texture data extracted from baseline F-FDG PET/CT studies performed initial staging of patient with esophageal cancer (EC), to pre...
Resistance to ionizing radiation, a first-line therapy for many cancers, is a major clinical challenge. Personalized prediction of tumor radiosensitivity is not currently implemented clinically due to insufficient accuracy of existing machine learnin...
AIM: Artificial intelligence (AI)-based breast cancer grading may help to overcome perceived limitations of human assessment. Here, the potential value of AI grade was evaluated at the molecular level and in predicting patient outcome.
INTRODUCTION: Recent studies have reported that HbA1c and lipid variability is useful for risk stratification in diabetes mellitus. The present study evaluated the predictive value of the baseline, subsequent mean of at least three measurements and v...
Advancements in sequencing have led to the proliferation of multi-omic profiles of human cells under different conditions and perturbations. In addition, many databases have amassed information about pathways and gene "signatures"-patterns of gene ex...
IEEE/ACM transactions on computational biology and bioinformatics
Apr 6, 2021
Survival analysis is a popular branch of statistics. At present, many algorithms (like traditional multi-tasking learning model) cannot be applied well in practice because of censored data. Although using some model (like parametric regression model)...