AIMC Topic: Transcriptome
Clear Filters Showing 731 to 740 of 928 articles
The Role of HbA1c in Parkinson's Disease: An Integrative Analysis by Single-Cell, Bulk Transcriptome and Mendelian Randomization.
Molecular neurobiology
Sep 1, 2025
Decreased glucose tolerance is recognized as a factor associated with Parkinson's disease (PD) progression, yet the relationship between HbA1c and PD prognosis remains insufficiently explored. Using data from the Integrated Epidemiological Unit (IEU)...
Transcriptome analysis and machine learning methods reveal potential mechanisms of zebrafish muscle aging.
Comparative biochemistry and physiology. Part D, Genomics & proteomics
Sep 1, 2025
Muscle is one of the most abundant tissues in the human body, and its aging usually leads to many adverse consequences. Zebrafish is a powerful model used to study human muscle diseases, yet we know little about the molecular mechanisms of muscle agi...
Identification of Npas4 as a biomarker for CICI by transcriptomics combined with bioinformatics and machine learning approaches.
Experimental neurology
Sep 1, 2025
Chemotherapy is one of the most successful strategies for treating cancer. Unfortunately, up to 70 % of cancer survivors develop cognitive impairment during or after chemotherapy, which severely affects their quality of life. We first established a m...
Deciphering the transcriptomic characteristic of lactate metabolism and the immune infiltration landscape in abdominal aortic aneurysm.
Biochemical and biophysical research communications
Aug 30, 2025
BACKGROUND: Abdominal aortic aneurysm (AAA) is a common degenerative vascular disease characterized by progressive dilation of the abdominal aorta, which poses a life-threatening risk upon rupture. Lactate, a key metabolic byproduct and immunomodulat...
Interspecies predictions of growth traits from quantitative transcriptome data acquired during fruit development.
Journal of experimental botany
Aug 21, 2025
Linking genotype and phenotype is a fundamental challenge in biology. In this respect, machine learning is playing a pivotal role in systems biology. As central phenotypic traits, fruit development and relative growth rate (RGR) result from interacti...
Hub biomarkers and their clinical relevance in glycometabolic disorders: A comprehensive bioinformatics and machine learning approach.
Chinese medical journal
Aug 20, 2025
BACKGROUND: Gluconeogenesis is a critical metabolic pathway for maintaining glucose homeostasis, and its dysregulation can lead to glycometabolic disorders. This study aimed to identify hub biomarkers of these disorders to provide a theoretical found...
Prediction of treatment efficacy in the suanzaoren decoction and estazolam for chronic insomnia disorder, along with brain function and cognitive changes before and after treatment, and potential gene expression profiles.
Asian journal of psychiatry
Aug 1, 2025
OBJECTIVE: This study compared the brain function changes in chronic insomnia disorder (CID) before and after treatment by suanzaoren decoction (SZRD) and estazolam, to reveal their effects in cognition improvement, and to explore the potential genet...
Mechanistic exploration of hexokinase 2 and metabolism in diabetic cardiomyopathy.
Molecular medicine reports
Aug 1, 2025
The pathogenesis of diabetic cardiomyopathy (DCM) remains incompletely understood. The present study employed weighted gene co‑expression network analysis to analyze the DCM transcriptome dataset from the Gene Expression Omnibus (GEO) database to ide...
Incorporating time as a third dimension in transcriptomic analysis using machine learning and explainable AI.
Computational biology and chemistry
Aug 1, 2025
Transcriptomic data analysis entails the measurement of RNA transcript (gene expression products) abundance in a cell or a cell population at a single point in time. In other words, transcriptomics as it is currently practiced is two-dimensional (2DT...
Multi-omics identifies OSM-OSMR as a key receptor-ligand in the tumor environment of endometrial adenocarcinoma.
International immunopharmacology
Jul 28, 2025
Endometrial adenocarcinoma carries a bleak prognosis, and the molecular markers that evaluate the progression of endometrial adenocarcinoma to advanced stages remain uncertain. Cell-cell communication plays a crucial role in the tumor microenvironmen...
Cell Proliferation
Signal Transduction
Adenocarcinoma
Mice
Multiomics
Gene Expression Regulation, Neoplastic
Oncostatin M
Oncostatin M Receptor beta Subunit
Mice, Nude
Ligands
Endometrial Neoplasms
Prognosis
Female
Tumor Microenvironment
Transcriptome
Cell Line, Tumor
Animals
Gene Expression Profiling
Humans
Stay Ahead of Medical AI
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 32510
- Neural Networks, Computer 30481
- Algorithms 27731
- Deep Learning 27277
- Artificial Intelligence 25203
- Robotics 13428
- Image Processing, Computer-Assisted 9883
- Retrospective Studies 9527
- Magnetic Resonance Imaging 6481
- Reproducibility of Results 5744
- Tomography, X-Ray Computed 4956
- Support Vector Machine 4812
- Computational Biology 4392
- Brain 4186
- Computer Simulation 3962
Recent Journals
- Scientific reports 7009
- Sensors (Basel, Switzerland) 4794
- PloS one 4295
- Neural networks : the official journal of the International Neural Network Society 3035
- Computers in biology and medicine 2037
- Computational intelligence and neuroscience 1931
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1395
- IEEE journal of biomedical and health informatics 1191
- Journal of chemical information and modeling 1083
- Nature communications 1070
- Computer methods and programs in biomedicine 895
- Bioinformatics (Oxford, England) 879
- Journal of medical Internet research 878
- IEEE transactions on neural networks and learning systems 859