AIMC Topic: Transcriptome

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What time is it? Deep learning approaches for circadian rhythms.

Bioinformatics (Oxford, England)
MOTIVATION: Circadian rhythms date back to the origins of life, are found in virtually every species and every cell, and play fundamental roles in functions ranging from metabolism to cognition. Modern high-throughput technologies allow the measureme...

Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes.

EBioMedicine
The ratio of monocytes and lymphocytes (ML ratio) in peripheral blood is associated with tuberculosis and malaria disease risk and cancer and cardiovascular disease outcomes. We studied anti-mycobacterial function and the transcriptome of monocytes i...

A genetic filter for cancer classification on gene expression data.

Bio-medical materials and engineering
We present a new genetic filter to identify a predictive gene subset for cancer-type classification on gene expression profiles. This approach pursues to not only maximize correlation between selected genes and cancer types but also minimize inter-co...