Alzheimer's & dementia : the journal of the Alzheimer's Association
Jun 6, 2022
INTRODUCTION: To test the utility of the "A/T/N" system in the Chinese population, we study core Alzheimer's disease (AD) biomarkers in a newly established Chinese cohort.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Apr 22, 2022
INTRODUCTION: We examined whether German claims data are suitable for dementia risk prediction, how machine learning (ML) compares to classical regression, and what the important predictors for dementia risk are.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Nov 10, 2021
We aimed to evaluate the value of ATN biomarker classification system (amyloid beta [A], pathologic tau [T], and neurodegeneration [N]) for predicting conversion from mild cognitive impairment (MCI) to dementia. In a sample of people with MCI (n = 41...
Alzheimer's & dementia : the journal of the Alzheimer's Association
Sep 13, 2020
INTRODUCTION: Relationships between brain atrophy patterns of typical aging and Alzheimer's disease (AD), white matter disease, cognition, and AD neuropathology were investigated via machine learning in a large harmonized magnetic resonance imaging d...
Alzheimer's & dementia : the journal of the Alzheimer's Association
Jul 30, 2020
INTRODUCTION: Identifying cognitively normal individuals at high risk for progression to symptomatic Alzheimer's disease (AD) is critical for early intervention.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Feb 11, 2020
INTRODUCTION: Developing cross-validated multi-biomarker models for the prediction of the rate of cognitive decline in Alzheimer's disease (AD) is a critical yet unmet clinical challenge.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Jun 11, 2019
INTRODUCTION: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Jun 1, 2025
INTRODUCTION: The study aimed to develop and validate the Emergency Department Dementia Algorithm (EDDA) to detect dementia among older adults (65+) and support clinical decision-making in the emergency department (ED).
Alzheimer's & dementia : the journal of the Alzheimer's Association
May 1, 2025
INTRODUCTION: Neurodegenerative diseases (NDDs) are chronic diseases caused by brain neuron degeneration, requiring systematic integration of risk factors to address their heterogeneity. Established in 2021, Knowledgebase of Risk Factors for Neurodeg...