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Adenosine

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[Determination of Nucleosides and Nucleobases in Natural, Cultured and Tissue Culture Anoectochilus roxburghii Using LC-MS].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
OBJECTIVE: To establish a method for simultaneous determination of nucleosides and nucleobases in natural, cultured and tissue culture Anoectochilus roxburghii by high performance liquid chromatography-electrospray ionization/ion trap mass spectromet...

Myocardial Fractional Flow Reserve Measurement Using Contrast Media as a First-Line Assessment of Coronary Lesions in Current Practice.

The Canadian journal of cardiology
BACKGROUND: Fractional flow reserve (FFR) measurement requires adenosine injection. However, adenosine can induce conductive and rhythmic complications, or be contraindicated in some patients. Contrast-induced hyperemia could provide a simple first-l...

Dynamic regulation of RNA editing in human brain development and disease.

Nature neuroscience
RNA editing is increasingly recognized as a molecular mechanism regulating RNA activity and recoding proteins. Here we surveyed the global landscape of RNA editing in human brain tissues and identified three unique patterns of A-to-I RNA editing rate...

TargetM6A: Identifying N-Methyladenosine Sites From RNA Sequences via Position-Specific Nucleotide Propensities and a Support Vector Machine.

IEEE transactions on nanobioscience
As one of the most ubiquitous post-transcriptional modifications of RNA, N-methyladenosine ( [Formula: see text]) plays an essential role in many vital biological processes. The identification of [Formula: see text] sites in RNAs is significantly imp...

Detecting N-methyladenosine sites from RNA transcriptomes using ensemble Support Vector Machines.

Scientific reports
As one of the most abundant RNA post-transcriptional modifications, N-methyladenosine (mA) involves in a broad spectrum of biological and physiological processes ranging from mRNA splicing and stability to cell differentiation and reprogramming. Howe...

Identifying N-methyladenosine sites using multi-interval nucleotide pair position specificity and support vector machine.

Scientific reports
N6-methyladenosine (mA) refers to methylation of the adenosine nucleotide acid at the nitrogen-6 position. It plays an important role in a series of biological processes, such as splicing events, mRNA exporting, nascent mRNA synthesis, nuclear transl...

Kinematics optimization and static analysis of a modular continuum robot used for minimally invasive surgery.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
For the outstanding compliance and dexterity of continuum robot, it is increasingly used in minimally invasive surgery. The wide workspace, high dexterity and strong payload capacity are essential to the continuum robot. In this article, we investiga...

BERMP: a cross-species classifier for predicting mA sites by integrating a deep learning algorithm and a random forest approach.

International journal of biological sciences
N-methyladenosine (mA) is a prevalent RNA methylation modification involved in several biological processes. Hundreds or thousands of mA sites identified from different species using high-throughput experiments provides a rich resource to construct ...

iMethyl-STTNC: Identification of N-methyladenosine sites by extending the idea of SAAC into Chou's PseAAC to formulate RNA sequences.

Journal of theoretical biology
N- methyladenosine (mA) is a vital post-transcriptional modification, which adds another layer of epigenetic regulation at RNA level. It chemically modifies mRNA that effects protein expression. RNA sequence contains many genetic code motifs (GAC). A...