AIMC Topic: Adult

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Integrating SHAP analysis with machine learning to predict postpartum hemorrhage in vaginal births.

BMC pregnancy and childbirth
OBJECTIVE: This study aimed to develop a machine learning (ML) model integrated with SHapley Additive exPlanations (SHAP) analysis to predict postpartum hemorrhage (PPH) following vaginal deliveries, offering a potential tool for personalized risk as...

Radiomic study of common sellar region lesions differentiation in magnetic resonance imaging based on multi-classification machine learning model.

BMC medical imaging
OBJECTIVE: Pituitary adenomas (PAs), craniopharyngiomas (CRs), Rathke's cleft cysts (RCCs), and tuberculum sellar meningiomas (TSMs) are common sellar region lesions with similar imaging characteristics, making differential diagnosis challenging. Thi...

Effects of exoskeleton rehabilitation robot training on neuroplasticity and lower limb motor function in patients with stroke.

BMC neurology
BACKGROUND: Lower limb exoskeleton rehabilitation robot is a new technology to improve the lower limb motor function of stroke patients. Recovery of motor function after stroke is closely related to neuroplasticity in the motor cortex and associated ...

Surgical and radiological outcomes of giant cell tumor of the bone: prognostic value of Campanacci grading and selective use of denosumab.

Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology
BACKGROUND: Advancements in diagnostic and therapeutic modalities for giant cell tumors of bone (GCTB) have introduced molecular and radiological tools that refine clinical decision-making. H3.3 G34W immunohistochemical staining has become a routine ...

Interpretable machine learning model for predicting post-hepatectomy liver failure in hepatocellular carcinoma.

Scientific reports
Post-hepatectomy liver failure (PHLF) is a severe complication following liver surgery. We aimed to develop a novel, interpretable machine learning (ML) model to predict PHLF. We enrolled 312 hepatocellular carcinoma (HCC) patients who underwent hepa...

Prediction of High-Dose Methotrexate Blood Concentration in Osteosarcoma Patients Using Machine Learning.

Drug design, development and therapy
INTRODUCTION: High-dose methotrexate is a typical chemotherapy that is widely used in the treatment of osteosarcoma. However, the unique dose-response relationship of methotrexate makes its treatment window relatively narrow, and its clinical use is ...

Multi-modal signal integration for enhanced sleep stage classification: Leveraging EOG and 2-channel EEG data with advanced feature extraction.

Artificial intelligence in medicine
This paper introduces an innovative approach to sleep stage classification, leveraging a multi-modal signal integration framework encompassing Electrooculography (EOG) and two-channel electroencephalography (EEG) data. We explore the utility of vario...

Machine learning approach to single cell transcriptomic analysis of Sjogren's disease reveals altered activation states of B and T lymphocytes.

Journal of autoimmunity
Sjogren's Disease (SjD) is an autoimmune disorder characterized by salivary and lacrimal gland dysfunction and immune cell infiltration leading to gland inflammation and destruction. Although SjD is a common disease, its pathogenesis is not fully und...

Testing theories of political persuasion using AI.

Proceedings of the National Academy of Sciences of the United States of America
Despite its importance to society and many decades of research, key questions about the social and psychological processes of political persuasion remain unanswered, often due to data limitations. We propose that AI tools, specifically generative lar...

GLIO-Select: Machine Learning-Based Feature Selection and Weighting of Tissue and Serum Proteomic and Metabolomic Data Uncovers Sex Differences in Glioblastoma.

International journal of molecular sciences
Glioblastoma (GBM) is a fatal brain cancer known for its rapid and aggressive growth, with some studies indicating that females may have better survival outcomes compared to males. While sex differences in GBM have been observed, the underlying biolo...