AIMC Topic: Adult

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Menopausal hormone therapy and the female brain: Leveraging neuroimaging and prescription registry data from the UK Biobank cohort.

eLife
BACKGROUND: Menopausal hormone therapy (MHT) is generally thought to be neuroprotective, yet results have been inconsistent. Here, we present a comprehensive study of MHT use and brain characteristics in females from the UK Biobank.

Exploring the medical ethical limitations of GPT-4 in clinical decision-making scenarios: a pilot survey.

Frontiers in public health
BACKGROUND: This study aims to conduct an examination of GPT-4's tendencies when confronted with ethical dilemmas, as well as to ascertain their ethical limitations within clinical decision-makings.

Contrastive functional connectivity defines neurophysiology-informed symptom dimensions in major depression.

Cell reports. Medicine
Major depressive disorder (MDD) is highly heterogeneous, posing challenges for effective treatment due to complex interactions between clinical symptoms and neurobiological features. To address this, we apply contrastive principal-component analysis ...

Deep learning for predicting invasive recurrence of ductal carcinoma in situ: leveraging histopathology images and clinical features.

EBioMedicine
BACKGROUND: Ductal Carcinoma In Situ (DCIS) can progress to ipsilateral invasive breast cancer (IBC) but over 75% of DCIS lesions do not progress if untreated. Currently, DCIS that might progress to IBC cannot reliably be identified. Therefore, most ...

Detecting Tardive Dyskinesia Using Video-Based Artificial Intelligence.

The Journal of clinical psychiatry
Tardive dyskinesia (TD) is a late-onset adverse effect of dopamine receptor-blocking medications, characterized by involuntary movements primarily affecting the mouth, though other body parts may be involved. Severity of TD varies from mild to debil...

Comparing orthodontic pre-treatment information provided by large language models.

BMC oral health
This study collected and screened the 50 most common pre-treatment consultation questions from adult orthodontic patients through clinical practice. Responses to these questions were generated using three large language models: Ernie Bot, ChatGPT, an...

Performance of a novel multimodal large language model in ınterpreting meibomian glands quantitatively and qualitatively.

International ophthalmology
PURPOSE: To evaluate the performance of a multimodal large language model (LLM), Claude 3.5 Sonnet, in interpreting meibography images for Meibomian gland dropout grading and morphological abnormality detection.

C2 pars interarticularis length on the side of high-riding vertebral artery with implications for pars screw insertion.

Scientific reports
C2 pars interarticularis length (C2PIL) required for pars screws has not been thoroughly studied in subjects with high-riding vertebral artery (HRVA). We aimed to measure C2PIL specifically on the sides with HRVA, define short pars, optimal pars scre...

Mechanisms and management of self-resolving lumbar disc herniation: bridging molecular pathways to non-surgical clinical success.

Journal of orthopaedic surgery and research
Spontaneous resorption of lumbar disk herniation (LDH) presents a promising avenue for the non-surgical management of herniated disks. Here we present a 40-year-old female with severe L5/S1 herniation who experienced spontaneous resorption confirmed ...

Dual-energy CT combined with histogram parameters in the assessment of perineural invasion in colorectal cancer.

International journal of colorectal disease
PURPOSE: The purpose is to evaluate the predictive value of dual-energy CT (DECT) combined with histogram parameters and a clinical prediction model for perineural invasion (PNI) in colorectal cancer (CRC).