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Mechanisms and management of self-resolving lumbar disc herniation: bridging molecular pathways to non-surgical clinical success.
Journal of orthopaedic surgery and research
May 27, 2025
Spontaneous resorption of lumbar disk herniation (LDH) presents a promising avenue for the non-surgical management of herniated disks. Here we present a 40-year-old female with severe L5/S1 herniation who experienced spontaneous resorption confirmed ...
Dual-energy CT combined with histogram parameters in the assessment of perineural invasion in colorectal cancer.
International journal of colorectal disease
May 27, 2025
PURPOSE: The purpose is to evaluate the predictive value of dual-energy CT (DECT) combined with histogram parameters and a clinical prediction model for perineural invasion (PNI) in colorectal cancer (CRC).
AI-based multimodal prediction of lymph node metastasis and capsular invasion in cT1N0M0 papillary thyroid carcinoma.
Frontiers in endocrinology
May 27, 2025
BACKGROUND: Accurate preoperative evaluation of cT1N0M0 papillary thyroid carcinoma (PTC) is essential for guiding appropriate treatment strategies. Although ultrasound is widely used for clinical staging, it has limitations in detecting lymph node m...
Development and validation of a LASSO logistic regression based nomogram for predicting live births in women with polycystic ovary syndrome: a retrospective cohort study.
Frontiers in endocrinology
May 27, 2025
OBJECTIVE: There is limited study on predictive models for live births in patients with polycystic ovarian syndrome (PCOS). The study aimed to develop and validate a nomogram for predicting live births in Chinese women with PCOS, as well as to identi...
Deep learning to promote health through sports and physical training.
Frontiers in public health
May 27, 2025
BACKGROUND: Physical activity plays a crucial role in maintaining health and preventing chronic diseases. However, accurately assessing the impact of sports and physical training on health improvement remains a challenge. Recent advancements in deep ...
Type 2 Diabetes in Taiwan: Unmasking Influential Factors Through Advanced Predictive Modeling.
Journal of diabetes research
May 27, 2025
Type 2 diabetes (T2D) is influenced by lifestyle, genetics, and environmental conditions. By utilizing machine learning techniques, we can enhance the precision of T2D risk prediction by analyzing the complex interactions among these variables. This...
Leveraging pre-vaccination antibody titres across multiple influenza H3N2 variants to forecast the post-vaccination response.
EBioMedicine
May 26, 2025
BACKGROUND: Despite decades of research on the influenza virus, we still lack a predictive understanding of how vaccination reshapes each person's antibody response, which impedes efforts to design better vaccines. Models using pre-vaccination antibo...
Study protocol for the Rainbow Austrian Longitudinal Family (RALF) study: a longitudinal, multi-method, multi-rater investigation of risk and resilience factors in Austrian LGBTQ+ parent families.
BMC psychology
May 26, 2025
BACKGROUND: Research on LGBTQ+ parent families is evolving to include a growing range of family systems, identities, methodologies, and topics. However, studies that examine minority-specific risk and resilience factors and their associations with wi...
Predicting treatment response in individuals with major depressive disorder using structural MRI-based similarity features.
BMC psychiatry
May 26, 2025
BACKGROUND: Major Depressive Disorder (MDD) is a prevalent mental health condition with significant societal impact. Structural magnetic resonance imaging (sMRI) and machine learning have shown promise in psychiatry, offering insights into brain abno...
The extent of Skeletal muscle wasting in prolonged critical illness and its association with survival: insights from a retrospective single-center study.
BMC anesthesiology
May 26, 2025
OBJECTIVE: Muscle wasting in critically ill patients, particularly those with prolonged hospitalization, poses a significant challenge to recovery and long-term outcomes. The aim of this study was to characterize long-term muscle wasting trajectories...
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