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Exploring potential methylation markers for ovarian cancer from cervical scraping samples.
Human genomics
May 17, 2025
BACKGROUND: Ovarian cancer has the highest mortality rate among gynecological cancers, making early detection crucial, as the five-year survival rate drops from 92% with early-stage diagnosis compared to 31% with late-stage diagnosis. Current diagnos...
A Point Cloud Generation Network for Automatic Prediction of Postoperative Maxillofacial Soft Tissue.
Annals of biomedical engineering
May 16, 2025
PURPOSE: In the planning of maxillofacial surgery, accurately evaluating the postoperative soft tissue area is crucial. This allows doctors to provide patients with better morphological recovery while ensuring the restoration of normal functional are...
Using the Language of elite athletes to predict their personality and on court transgressions.
Scientific reports
May 16, 2025
Personality is predictive of many behaviors, but personality questionnaires cannot be readily administered to persons of interest. The language people use to express themselves can often predict personality and so should, in theory, provide a surroga...
AI-assisted diffuse correlation tomography for identifying breast cancer.
Journal of biomedical optics
May 16, 2025
SIGNIFICANCE: Diffuse correlation tomography (DCT) is an emerging technique for the noninvasive measurement of breast microvascular blood flow, whereas its capability to categorize benign and malignant breast lesions has not been extensively validate...
Developing cardiac digital twin populations powered by machine learning provides electrophysiological insights in conduction and repolarization.
Nature cardiovascular research
May 16, 2025
Large-cohort imaging and diagnostic studies often assess cardiac function but overlook underlying biological mechanisms. Cardiac digital twins (CDTs) are personalized physics-constrained and physiology-constrained in silico representations, uncoverin...
Serologic biomarker discovery for differentiating Lyme disease from diseases with similar clinical symptoms using broad profiling of antibody binding.
Frontiers in immunology
May 16, 2025
INTRODUCTION: Lyme disease (LD) is a tick-borne disease that is a substantial public health burden with estimated about 0.5 million new cases per year in the US and increasing incidence. Differentiating Lyme disease, especially in its early stages, f...
Robust performances of a nocturnal long-term ECG algorithm for the evaluation of sleep apnea syndrome: A pilot study.
PloS one
May 16, 2025
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is one of the most common sleep disorders affecting nearly one billion of the global adult population, making it a major public health issue. Even if in-lab polysomnography (PSG) remains the gold stan...
Predicting infections with multidrug-resistant organisms (MDROs) in neurocritical care patients with hospital-acquired pneumonia (HAP): development of a novel multivariate prediction model.
Microbiology spectrum
May 15, 2025
Hospital-acquired pneumonia (HAP) is prevalent in the neuro-intensive care unit (NICU), significantly increasing susceptibility to infections with multidrug-resistant organisms (MDROs), which result in high mortality rates and substantial healthcare ...
Potential Modulatory Roles of Gut Microbiota and Metabolites in the Associations of Macronutrient-to-Physical Activity Ratios With Dyslipidemia.
Journal of the American Heart Association
May 15, 2025
BACKGROUND: Lifestyle factors toward diet and physical activity (PA) may directly influence the pathophysiology of dyslipidemia. However, the associations of the specific macronutrient-to-PA ratio with dyslipidemia, and the underlying mechanisms rega...
Automated high precision PCOS detection through a segment anything model on super resolution ultrasound ovary images.
Scientific reports
May 15, 2025
PCOS (Poly-Cystic Ovary Syndrome) is a multifaceted disorder that often affects the ovarian morphology of women of their reproductive age, resulting in the development of numerous cysts on the ovaries. Ultrasound imaging typically diagnoses PCOS, whi...
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