AIMC Topic: Aged, 80 and over

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Deep-learning based multi-modal models for brain age, cognition and amyloid pathology prediction.

Alzheimer's research & therapy
BACKGROUND: Magnetic resonance imaging (MRI), combined with artificial intelligence techniques, has improved our understanding of brain structural change and enabled the estimation of brain age. Neurodegenerative disorders, such as Alzheimer's diseas...

Machine learning based prediction of cognitive metrics using major biomarkers in SuperAgers.

Scientific reports
As populations age, understanding cognitive decline and age-related diseases like dementia has become increasingly important. "SuperAgers," individuals over 65 with cognitive abilities similar to those in their 40s, provide a unique perspective on co...

Predicting cognitive frailty in community-dwelling older adults: a machine learning approach based on multidomain risk factors.

Scientific reports
Cognitive frailty (CF), a clinical syndrome involving both physical frailty (PF) and impaired cognition (IC), is associated with adverse health outcomes in older adults. This study aimed to identify key predictors of CF and develop a machine learning...

Feasibility and Effects of a Gait Assistance and Gait Resistance Training Program Using a Walking-Assist Wearable Robot for Community-Dwelling Older Adults: Single-Group, Pre-, and Posttest Study.

JMIR mHealth and uHealth
BACKGROUND: Two-thirds of people aged 65 years and older may require help with daily activities such as eating, bathing, and getting in and out of bed or a chair. Walking-assist wearable robots have shown significant improvements in physical function...

Predicting the risk of ibrutinib in combination with R-ICE in patients with relapsed or refractory DLBCL using explainable machine learning algorithms.

Clinical and experimental medicine
Relapsed or refractory diffuse large B-cell lymphoma (DLBCL) poses significant therapeutic challenges due to heterogeneous patient outcomes. This study aimed to evaluate the efficacy of the ibrutinib plus R-ICE regimen and to leverage explainable mac...

Machine learning model for prediction of palliative care phases in patients with advanced cancer: a retrospective study.

BMC palliative care
BACKGROUND: Developing an accurate predictive model for palliative care phases is crucial for improving cancer patient management, enabling healthcare providers to identify those in need of specific care plans and streamlining decision-making process...