AIMC Topic: Aged

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Latent feature representation with stacked auto-encoder for AD/MCI diagnosis.

Brain structure & function
Recently, there have been great interests for computer-aided diagnosis of Alzheimer's disease (AD) and its prodromal stage, mild cognitive impairment (MCI). Unlike the previous methods that considered simple low-level features such as gray matter tis...

Machine Learning-Based Prediction of Distant Recurrence Risk and Ribociclib Treatment Effect in HR+/HER2- Early Breast Cancer Using Real-World and NATALEE Data.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: Despite current standard-of-care endocrine therapy, distant recurrence remains a concern for patients with hormone receptor-positive (HR+)/HER2- early breast cancer (EBC). Understanding individual recurrence risk would aid in clinical decisi...

[Geriatric hip fracture and enhanced recovery after surgery: current status and future perspectives].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
In recent years, considerable progress has been made in the specific development and practice of enhanced recovery after surgery (ERAS) for geriatric hip fracture domestically and internationally. By synthesizing domestic and international research r...

Predicting high lymph node positivity risk factors in nasopharyngeal carcinoma patients: A multi-model approach.

Medicine
Identifying patients at high risk of an elevated lymph node ratio (LNR) is critical for optimizing the management of nasopharyngeal carcinoma (NPC), as LNR, defined as the ratio of metastatic to examined lymph nodes, serves as a key prognostic indica...

[An objective overview of lifestyle and quality of life in the Spanish population: a quantification of nutri-indices and qualitative health nutritypes].

Nutricion hospitalaria
Introduction: precision nutritional epidemiology studies require the development of initiatives to obtain objective population data that enable the implementation of health strategies. Therefore, the integration of health determinants and risk factor...

T-cell Subset Features and Distributions Evolve across the Colorectal Precancer-Cancer Spectrum.

Cancer immunology research
The immune microenvironment is a crucial component of colorectal carcinoma that has been well characterized, but much less is known about the immune microenvironment of colorectal carcinoma precursors. We hypothesized that T-cell infiltrates might di...

Diagnosing migraine from genome-wide genotype data: a machine learning analysis.

Brain : a journal of neurology
Migraine has an assumed polygenic basis, but the genetic risk variants identified in genome-wide association studies only explain a proportion of the heritability. We aimed to develop machine learning models, capturing non-additive and interactive ef...