AIMC Topic: Aged

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Multi-site validation of an interpretable model to analyze breast masses.

PloS one
An external validation of IAIA-BL-a deep-learning based, inherently interpretable breast lesion malignancy prediction model-was performed on two patient populations: 207 women ages 31 to 96, (425 mammograms) from iCAD, and 58 women (104 mammograms) f...

Progression and natural history of Atypical Parkinsonism (ATPARK): Protocol for a longitudinal follow-up study from an underrepresented population.

PloS one
BACKGROUND: Atypical Parkinsonian Syndromes (APS) form the third largest group of neurodegenerative disorders including Progressive Supranuclear Palsy (PSP), Multiple System Atrophy (MSA), and Corticobasal Syndrome (CBS). These conditions are charact...

Multi-parameter MRI deep learning model for lymphovascular invasion assessment in invasive breast ductal carcinoma: A multicenter, retrospective study.

Clinical radiology
AIMS: To investigate the value of multi-parametric magnetic resonance imaging (MRI)-based deep learning (DL) in predicting the Lymphovascular Invasion (LVI) status of invasive breast ductal cancer (IBDC).

Computed tomography-derived quantitative imaging biomarkers enable the prediction of disease manifestations and survival in patients with systemic sclerosis.

RMD open
INTRODUCTION: Systemic sclerosis (SSc) is a complex inflammatory vasculopathy with diverse symptoms and variable disease progression. Despite its known impact on body composition (BC), clinical decision-making has yet to incorporate these biomarkers....

Impact of mHealth on Postoperative Quality of Life, Self-Management, and Dysfunction in Patients With Oral and Maxillofacial Tumors: Nonrandomized Controlled Trial.

JMIR mHealth and uHealth
BACKGROUND: With a focus on postoperative dysfunctions that may occur after maxillofacial tumor resection and the difficulties faced during home rehabilitation, we developed a mobile health app based on nurse-patient cooperation. The app extends reha...

Using a Multilingual AI Care Agent to Reduce Disparities in Colorectal Cancer Screening for Higher Fecal Immunochemical Test Adoption Among Spanish-Speaking Patients: Retrospective Analysis.

Journal of medical Internet research
BACKGROUND: Colorectal cancer (CRC) screening rates remain disproportionately low among Hispanic and Latino populations compared to non-Hispanic White populations. While artificial intelligence (AI) shows promise in health care delivery, concerns exi...

Regional free-water diffusion is more strongly related to neuroinflammation than neurodegeneration.

Journal of neurology
INTRODUCTION: Recent research has suggested that neuroinflammation may be important in the pathogenesis of neurodegenerative diseases. Free-water diffusion (FWD) has been proposed as a non-invasive neuroimaging-based biomarker for neuroinflammation.

Construction of a novel online calculator for prediction of osteoporosis risk in Chinese type 2 diabetes patients.

Experimental gerontology
BACKGROUND: Type 2 diabetes (T2D) has been established as an independent risk factor for osteoporosis, often resulting in a poor prognosis. Thus, it is crucial for clinicians to diagnose osteoporosis in diabetic patients. This study aimed to develop ...

Relative importance of key life domains in explaining life satisfaction among older adults.

Journal of psychosomatic research
OBJECTIVE: Life satisfaction is a key element contributing to successful aging. Limited empirical studies have specifically explored the nature of the relationship between domain-specific satisfaction and global life satisfaction among older adults. ...

Comprehensive predictive modeling in subarachnoid hemorrhage: integrating radiomics and clinical variables.

Neurosurgical review
Subarachnoid hemorrhage (SAH) is a severe condition with high morbidity and long-term neurological consequences. Radiomics, by extracting quantitative features from Computed Tomograhpy (CT) scans, may reveal imaging biomarkers predictive of outcomes....