Brain and nerve = Shinkei kenkyu no shinpo
Nov 1, 2021
Alzheimer's disease (AD) is a leading cause of dementia, and the current diagnostic methods of AD, such as positron emission tomography imaging, have a high cost and poor accessibility. Amyloidβ accumulates in the brain long before the symptomatic on...
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
Mar 1, 2021
OBJECTIVE: A predictive model of Alzheimer's disease (AD) was established based on brain surface meshes and geometric deep learning, and its performance was evaluated.
Database : the journal of biological databases and curation
Feb 16, 2021
Omics technologies offer great promises for improving our understanding of diseases. The integration and interpretation of such data pose major challenges, calling for adequate knowledge models. Disease maps provide curated knowledge about disorders'...
Proceedings of the National Academy of Sciences of the United States of America
Jan 19, 2021
Exon splicing triggered by unpredicted genetic mutation can cause translational variations in neurodegenerative disorders. In this study, we discover Alzheimer's disease (AD)-specific single-nucleotide variants (SNVs) and abnormal exon splicing of ph...
Cerebral cortex (New York, N.Y. : 1991)
Jan 5, 2021
Functional connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. A brain network, also named as connectome, could form a graph structure naturally, the nodes ...
BACKGROUND: It is desirable to achieve acceptable accuracy for computer aided diagnosis system (CADS) to disclose the dementia-related consequences on the brain. Therefore, assessing and measuring these impacts is fundamental in the diagnosis of deme...
The journal of prevention of Alzheimer's disease
Jan 1, 2021
BACKGROUND: It is important to use outcome measures for novel interventions in Alzheimer's disease (AD) that capture the research participants' views of effectiveness. The electronic Person-Specific Outcome Measure (ePSOM) development programme is un...
BACKGROUND: The transition from mild cognitive impairment (MCI) to dementia is of great interest to clinical research on Alzheimer's disease and related dementias. This phenomenon also serves as a valuable data source for quantitative methodological ...
BACKGROUND: Alzheimer's disease (AD) is one of many common neurodegenerative diseases without ideal treatment, but early detection and intervention can prevent the disease progression.
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