AIMC Topic: Angiogenesis Inhibitors
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Prediction of prognosis of immune checkpoint inhibitors combined with anti-angiogenic agents for unresectable hepatocellular carcinoma by machine learning-based radiomics.
BMC cancer
May 19, 2025
OBJECTIVES: This study aims to develop and validate a novel radiomics model utilizing magnetic resonance imaging (MRI) to predict progression-free survival (PFS) in patients with unresectable hepatocellular carcinoma (uHCC) who are receiving a combin...
Retrospective Studies
Female
Aged
Adult
Radiomics
Humans
Machine Learning
Prognosis
Nomograms
Angiogenesis Inhibitors
Antineoplastic Combined Chemotherapy Protocols
Magnetic Resonance Imaging
Progression-Free Survival
Male
Middle Aged
Liver Neoplasms
Carcinoma, Hepatocellular
Immune Checkpoint Inhibitors
Multi-Omics Integration With Machine Learning Identified Early Diabetic Retinopathy, Diabetic Macula Edema and Anti-VEGF Treatment Response.
Translational vision science & technology
Dec 2, 2024
PURPOSE: Identify optimal metabolic features and pathways across diabetic retinopathy (DR) stages, develop risk models to differentiate diabetic macular edema (DME), and predict anti-vascular endothelial growth factor (anti-VEGF) therapy response.
Prediction of Post-Treatment Visual Acuity in Age-Related Macular Degeneration Patients With an Interpretable Machine Learning Method.
Translational vision science & technology
Sep 3, 2024
PURPOSE: We evaluated the features predicting visual acuity (VA) after one year in neovascular age-related macular degeneration (nAMD) patients.
IMPACT OF RESIDUAL SUBRETINAL FLUID VOLUMES ON TREATMENT OUTCOMES IN A SUBRETINAL FLUID-TOLERANT TREAT-AND-EXTEND REGIMEN.
Retina (Philadelphia, Pa.)
Nov 1, 2021
PURPOSE: To investigate associations between residual subretinal fluid (rSRF) volumes, quantified using artificial intelligence and treatment outcomes in a subretinal fluid (SRF)-tolerant treat-and-extend (T&E) regimen in neovascular age-related macu...
Subretinal Fluid
Drug Tolerance
Follow-Up Studies
Visual Acuity
Tomography, Optical Coherence
Fundus Oculi
Vascular Endothelial Growth Factor A
Intravitreal Injections
Fluorescein Angiography
Ranibizumab
Wet Macular Degeneration
Humans
Artificial Intelligence
Prospective Studies
Angiogenesis Inhibitors
Treatment Outcome
Artificial intelligence-based predictions in neovascular age-related macular degeneration.
Current opinion in ophthalmology
Sep 1, 2021
PURPOSE OF REVIEW: Predicting treatment response and optimizing treatment regimen in patients with neovascular age-related macular degeneration (nAMD) remains challenging. Artificial intelligence-based tools have the potential to increase confidence ...
Automated Quantification of Pathological Fluids in Neovascular Age-Related Macular Degeneration, and Its Repeatability Using Deep Learning.
Translational vision science & technology
Apr 1, 2021
PURPOSE: To develop a reliable algorithm for the automated identification, localization, and volume measurement of exudative manifestations in neovascular age-related macular degeneration (nAMD), including intraretinal (IRF), subretinal fluid (SRF), ...
Investigating the anti-angiogenic effects of Fufang Kushen Injection in combination with cisplatin using a zebrafish model.
Pakistan journal of pharmaceutical sciences
Sep 1, 2020
The Traditional Chinese Medicine formula Fufang Kushen Injection (FKI) has demonstrated potential to enhance the efficacy and reduce the toxicity of the chemotherapeutic drug cisplatin. However, there is insufficient evidence to determine whether the...
Quantification of Fluid Resolution and Visual Acuity Gain in Patients With Diabetic Macular Edema Using Deep Learning: A Post Hoc Analysis of a Randomized Clinical Trial.
JAMA ophthalmology
Sep 1, 2020
IMPORTANCE: Large amounts of optical coherence tomographic (OCT) data of diabetic macular edema (DME) are acquired, but many morphologic features have yet to be identified and quantified.
Middle Aged
Deep Learning
Angiogenesis Inhibitors
Follow-Up Studies
Visual Acuity
Macular Edema
Vascular Endothelial Growth Factor A
Intravitreal Injections
Recombinant Fusion Proteins
Algorithms
Retrospective Studies
Female
Aged
Male
Humans
Diabetic Retinopathy
Ranibizumab
Receptors, Vascular Endothelial Growth Factor
Subretinal Fluid
Characterization of Drusen and Hyperreflective Foci as Biomarkers for Disease Progression in Age-Related Macular Degeneration Using Artificial Intelligence in Optical Coherence Tomography.
JAMA ophthalmology
Jul 1, 2020
IMPORTANCE: The morphologic changes and their pathognomonic distribution in progressing age-related macular degeneration (AMD) are not well understood.
The retina revolution: signaling pathway therapies, genetic therapies, mitochondrial therapies, artificial intelligence.
Current opinion in ophthalmology
May 1, 2020
PURPOSE OF REVIEW: The aim of this article is to review and discuss the history, current state, and future implications of promising biomedical offerings in the field of retina.
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