AIMC Topic: Angiogenesis Inhibitors
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IMPACT OF RESIDUAL SUBRETINAL FLUID VOLUMES ON TREATMENT OUTCOMES IN A SUBRETINAL FLUID-TOLERANT TREAT-AND-EXTEND REGIMEN.
Retina (Philadelphia, Pa.)
Nov 1, 2021
PURPOSE: To investigate associations between residual subretinal fluid (rSRF) volumes, quantified using artificial intelligence and treatment outcomes in a subretinal fluid (SRF)-tolerant treat-and-extend (T&E) regimen in neovascular age-related macu...
Angiogenesis Inhibitors
Treatment Outcome
Follow-Up Studies
Visual Acuity
Humans
Artificial Intelligence
Prospective Studies
Tomography, Optical Coherence
Fluorescein Angiography
Fundus Oculi
Ranibizumab
Vascular Endothelial Growth Factor A
Intravitreal Injections
Wet Macular Degeneration
Subretinal Fluid
Drug Tolerance
Artificial intelligence-based predictions in neovascular age-related macular degeneration.
Current opinion in ophthalmology
Sep 1, 2021
PURPOSE OF REVIEW: Predicting treatment response and optimizing treatment regimen in patients with neovascular age-related macular degeneration (nAMD) remains challenging. Artificial intelligence-based tools have the potential to increase confidence ...
Automated Quantification of Pathological Fluids in Neovascular Age-Related Macular Degeneration, and Its Repeatability Using Deep Learning.
Translational vision science & technology
Apr 1, 2021
PURPOSE: To develop a reliable algorithm for the automated identification, localization, and volume measurement of exudative manifestations in neovascular age-related macular degeneration (nAMD), including intraretinal (IRF), subretinal fluid (SRF), ...
Investigating the anti-angiogenic effects of Fufang Kushen Injection in combination with cisplatin using a zebrafish model.
Pakistan journal of pharmaceutical sciences
Sep 1, 2020
The Traditional Chinese Medicine formula Fufang Kushen Injection (FKI) has demonstrated potential to enhance the efficacy and reduce the toxicity of the chemotherapeutic drug cisplatin. However, there is insufficient evidence to determine whether the...
Quantification of Fluid Resolution and Visual Acuity Gain in Patients With Diabetic Macular Edema Using Deep Learning: A Post Hoc Analysis of a Randomized Clinical Trial.
JAMA ophthalmology
Sep 1, 2020
IMPORTANCE: Large amounts of optical coherence tomographic (OCT) data of diabetic macular edema (DME) are acquired, but many morphologic features have yet to be identified and quantified.
Angiogenesis Inhibitors
Follow-Up Studies
Visual Acuity
Macular Edema
Aged
Male
Middle Aged
Deep Learning
Receptors, Vascular Endothelial Growth Factor
Subretinal Fluid
Vascular Endothelial Growth Factor A
Intravitreal Injections
Recombinant Fusion Proteins
Ranibizumab
Humans
Diabetic Retinopathy
Algorithms
Retrospective Studies
Female
Characterization of Drusen and Hyperreflective Foci as Biomarkers for Disease Progression in Age-Related Macular Degeneration Using Artificial Intelligence in Optical Coherence Tomography.
JAMA ophthalmology
Jul 1, 2020
IMPORTANCE: The morphologic changes and their pathognomonic distribution in progressing age-related macular degeneration (AMD) are not well understood.
The retina revolution: signaling pathway therapies, genetic therapies, mitochondrial therapies, artificial intelligence.
Current opinion in ophthalmology
May 1, 2020
PURPOSE OF REVIEW: The aim of this article is to review and discuss the history, current state, and future implications of promising biomedical offerings in the field of retina.
Application of Artificial Intelligence in Targeting Retinal Diseases.
Current drug targets
Jan 1, 2020
Retinal diseases affect an increasing number of patients worldwide because of the aging population. Request for diagnostic imaging in ophthalmology is ramping up, while the number of specialists keeps shrinking. Cutting-edge technology embedding arti...
Deep Learning Predicts OCT Measures of Diabetic Macular Thickening From Color Fundus Photographs.
Investigative ophthalmology & visual science
Mar 1, 2019
PURPOSE: To develop deep learning (DL) models for the automatic detection of optical coherence tomography (OCT) measures of diabetic macular thickening (MT) from color fundus photographs (CFPs).
Photography
Intravitreal Injections
Diagnostic Techniques, Ophthalmological
Macula Lutea
Ranibizumab
Macular Edema
Vascular Endothelial Growth Factor A
Image Interpretation, Computer-Assisted
False Positive Reactions
Neural Networks, Computer
Retrospective Studies
Female
Sensitivity and Specificity
Humans
Diabetic Retinopathy
Randomized Controlled Trials as Topic
Male
Predictive Value of Tests
Middle Aged
Tomography, Optical Coherence
Deep Learning
Fundus Oculi
Angiogenesis Inhibitors
[Deep learning to support therapy decisions for intravitreal injections].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Sep 1, 2018
Significant progress has been made in artificial intelligence and computer vision research in recent years. Machine learning methods excel in a wide variety of tasks where sufficient data are available. We describe the application of a deep convoluti...
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