Hundreds of loci have been robustly associated with obesity-related traits, but functional characterization of candidate genes remains a bottleneck. Aiming to systematically characterize candidate genes for a role in accumulation of lipids in adipocy...
Inferring and understanding the underlying connectivity structure of a system solely from the observed activity of its constituent components is a challenge in many areas of science. In neuroscience, techniques for estimating connectivity are paramou...
Journal of the science of food and agriculture
Feb 12, 2025
BACKGROUND: Silkworm pupae (SP), the pupal stage of an edible insect, have strong potential in the food, medicine, and cosmetic industries. Sex sorting is essential to enhance nutritional content and genetic traits in SP crossbreeding but it remains ...
In single-cell transcriptomics research, accurately predicting cell lineage allocation and identifying differences between lineages are crucial for understanding cell differentiation processes and reducing early pregnancy miscarriages in humans. This...
Lameness detection in horses is a critical challenge in equine veterinary practice, particularly when symptoms are mild. This study aimed to develop a predictive system using a support vector machine (SVM) to identify the affected limb in horses trot...
We propose a robot-assisted method to generate spherical thermal lesions by high-intensity focused ultrasound (HIFU) ablation. Typically, HIFU-induced thermal lesions are cigar-shaped because the acoustic field in the focal area has a similar elongat...
UNLABELLED: This study aims to explore the regulatory role of cuproptosis in carotid intimal hyperplasia (IH), providing new insights into its pathophysiological mechanisms and potential diagnostic and therapeutic strategies.
In biomimetic design, researchers recreate existing biological structures to form functional devices. For biohybrid robotic swimmers assembled with tissue engineering, this is problematic because most devices operate at different length scales than t...
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
Feb 11, 2025
Microglia serve as vital innate immune cells in the central nervous system, playing crucial roles in the generation and development of brain neurons, as well as mediating a series of immune and inflammatory responses. The morphologic transitions of m...
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