Spinal cord injury (SCI) remains a significant clinical challenge and poses a dramatic threat to the life quality of patients due to limited neural regeneration and detrimental post-injury alternations in tissue microenvironment. We developed a thera...
Honey bees are essential pollinators of ecosystems and agriculture worldwide. With an estimated 50-80% of crops pollinated by honey bees, they generate approximately $20 billion annually in market value in the U.S. alone. However, commercial beekeepe...
Parkinson's disease (PD), a progressive neurodegenerative disorder, presents complex motor symptoms and lacks effective disease-modifying treatments. Here we show that integrating artificial intelligence (AI) with optogenetic intervention, termed opt...
In vitro gas production (GP) is commonly used to evaluate ruminant feed, yet its accurate interpretation requires robust mathematical modeling. This study systematically explores a wide array of nonlinear models to explain GP dynamics across various ...
Understanding how individual differences influence vulnerability to disease and responses to pharmacological treatments represents one of the main challenges in behavioral neuroscience. Nevertheless, inter-individual variability and sex-specific patt...
ripple bugs use specialized middle-leg fans with a flat-ribbon architecture to navigate the surfaces of fast-moving streams. We show that the fan's directional stiffness enables fast, passive elastocapillary morphing, independent of muscle input. Th...
Analytical methods : advancing methods and applications
Aug 21, 2025
Dry eye disease (DED) and depression exhibit high comorbidity, yet lipid and purine diagnostic biomarkers for depression-related DED remain unidentified. In this study, matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI)...
Aquatic ecosystems vital to biodiversity and climate change-such as coral reefs, kelp forests, and mangrove forests-are often cluttered with natural obstacles. To navigate these complex habitats, fish have evolved relatively small body sizes and outs...
Drone-based aerial monitoring can play a pivotal role in scaling up efforts to monitor species at risk. In this study, we assessed the population size, occupancy, and spatial interactions of gharials and muggers in the Eastern Rapti River and its tri...
International journal of pharmaceutics
Aug 20, 2025
Chronic wounds represent a significant healthcare challenge characterized by complex pathophysiology and poor clinical outcomes. The latest progress in smart bioelectronic systems which include biosensing capabilities alongside controlled drug delive...
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