AIMC Topic: Aspartate Aminotransferases
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Development and Validation of an Algorithm to Identify Nonalcoholic Fatty Liver Disease in the Electronic Medical Record.
Digestive diseases and sciences
Nov 4, 2015
BACKGROUND AND AIMS: Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Risk factors for NAFLD disease progression and liver-related outcomes remain incompletely understood due to the lack of computa...
International Classification of Diseases
Triglycerides
Cohort Studies
Logistic Models
United States
Aged
Biopsy
Diabetes Mellitus
Adult
Humans
Natural Language Processing
Non-alcoholic Fatty Liver Disease
Male
Algorithms
Middle Aged
Data Collection
Prevalence
Electronic Health Records
Alanine Transaminase
Female
Aspartate Aminotransferases
An APRI+ALBI-Based Multivariable Model as a Preoperative Predictor for Posthepatectomy Liver Failure.
Annals of surgery
May 1, 2025
OBJECTIVE AND BACKGROUND: Clinically significant posthepatectomy liver failure (PHLF B+C) remains the main cause of mortality after major hepatic resection. This study aimed to establish an aspartate aminotransferase to platelet ratio combined with a...
Liver Function Tests
Liver Failure
Preoperative Period
Serum Albumin
Predictive Learning Models
Platelet Count
Aspartate Aminotransferases
Bilirubin
Hepatectomy
Databases, Factual
Female
Aged
Male
Middle Aged
Risk Assessment
Postoperative Complications
ROC Curve
Predictive Value of Tests
Area Under Curve
Humans
Machine learning-based models for advanced fibrosis in non-alcoholic steatohepatitis patients: A cohort study.
World journal of gastroenterology
Mar 7, 2025
BACKGROUND: The global prevalence of non-alcoholic steatohepatitis (NASH) and its associated risk of adverse outcomes, particularly in patients with advanced liver fibrosis, underscores the importance of early and accurate diagnosis.
Development and Validation of a Novel Model to Discriminate Idiosyncratic Drug-Induced Liver Injury and Autoimmune Hepatitis.
Liver international : official journal of the International Association for the Study of the Liver
Feb 1, 2025
BACKGROUND AND AIM: Discriminating between idiosyncratic drug-induced liver injury (DILI) and autoimmune hepatitis (AIH) is critical yet challenging. We aim to develop and validate a machine learning (ML)-based model to aid in this differentiation.
Using machine learning to predict patients with polycystic ovary disease in Chinese women.
Taiwanese journal of obstetrics & gynecology
Jan 1, 2025
OBJECTIVE: With an estimated global frequency ranging from5 % to 21 %, polycystic ovary syndrome (PCOS) is one of the most prevalent hormonal disorders. There are many factors found to be related to PCOS. However, most of these researches used tradit...
Clinical significance of hepatic function in Graves disease with type 2 diabetic mellitus: A single-center retrospective cross-sectional study in Taiwan.
Medicine
Aug 26, 2022
Graves disease (GD) and type 2 diabetes mellitus (T2DM) both impair liver function; we therefore explored the possibility of a relationship among diabetic control, thyroid function, and liver function. This retrospective, cross-sectional study compar...
Development and validation of an ensemble machine learning framework for detection of all-cause advanced hepatic fibrosis: a retrospective cohort study.
The Lancet. Digital health
Mar 1, 2022
BACKGROUND: Cirrhosis is the result of advanced scarring (or fibrosis) of the liver, and is often diagnosed once decompensation with associated complications has occurred. Current non-invasive tests to detect advanced liver fibrosis have limited perf...
Effect of compound Yindan decoction on alpha-naphthylisothiocyanate-Induced acute intrahepatic cholestasis in rats.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Jun 1, 2019
OBJECTIVE: To investigate the therapeutic mechanism of compound Yindan decoction (CYD) in a rat model of acute intrahepatic cholestatic (AIC).
The Hepatoprotective Effect of Clidemia hirta against Carbon Tetrachloride (CCl4)-Induced Oxidative Stress and Hepatic Damage in Mice.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer
Jan 1, 2017
Liver diseases still represents a major health burden worldwide. Moreover, medicinal plants have gained popularity in the treatment of several diseases, including liver disease. Clidemia hirta possesses many medicinal properties for healing several d...
Antioxidant and hepatoprotective activities of Dicoma anomala Sond. aqueous root extract against carbon tetrachloride-induced liver damage in Wistar rats.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Aug 1, 2016
OBJECTIVE: To evaluates the antioxidant and hepatoprotective potentials of Dicoma anomala Sond. (Asteraceae) on body weight, feed and water intake, biochemical parameters and organ histology.
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