AIMC Topic: Automation

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Generating automated kidney transplant biopsy reports combining molecular measurements with ensembles of machine learning classifiers.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
We previously reported a system for assessing rejection in kidney transplant biopsies using microarray-based gene expression data, the Molecular Microscope Diagnostic System (MMDx). The present study was designed to optimize the accuracy and stabilit...

LeukocyteMask: An automated localization and segmentation method for leukocyte in blood smear images using deep neural networks.

Journal of biophotonics
Digital pathology and microscope image analysis is widely used in comprehensive studies of cell morphology. Identification and analysis of leukocytes in blood smear images, acquired from bright field microscope, are vital for diagnosing many diseases...

A convolutional neural network algorithm for automatic segmentation of head and neck organs at risk using deep lifelong learning.

Medical physics
PURPOSE: This study suggests a lifelong learning-based convolutional neural network (LL-CNN) algorithm as a superior alternative to single-task learning approaches for automatic segmentation of head and neck (OARs) organs at risk.

Automated classification of hepatocellular carcinoma differentiation using multiphoton microscopy and deep learning.

Journal of biophotonics
In the case of hepatocellular carcinoma (HCC) samples, classification of differentiation is crucial for determining prognosis and treatment strategy decisions. However, a label-free and automated classification system for HCC grading has not been yet...

Automated segmentation of 2D low-dose CT images of the psoas-major muscle using deep convolutional neural networks.

Radiological physics and technology
The psoas-major muscle has been reported as a predictive factor of sarcopenia. The cross-sectional area (CSA) of the psoas-major muscle in axial images has been indicated to correlate well with the whole-body skeletal muscle mass. In this study, we e...

Automatic localization and identification of mitochondria in cellular electron cryo-tomography using faster-RCNN.

BMC bioinformatics
BACKGROUND: Cryo-electron tomography (cryo-ET) enables the 3D visualization of cellular organization in near-native state which plays important roles in the field of structural cell biology. However, due to the low signal-to-noise ratio (SNR), large ...

Automated tumour budding quantification by machine learning augments TNM staging in muscle-invasive bladder cancer prognosis.

Scientific reports
Tumour budding has been described as an independent prognostic feature in several tumour types. We report for the first time the relationship between tumour budding and survival evaluated in patients with muscle invasive bladder cancer. A machine lea...

DeepIon: Deep learning approach for classifying ion transporters and ion channels from membrane proteins.

Journal of computational chemistry
The movement of ions across the cell membrane is an essential for many biological processes. This study is focused on ion channels and ion transporters (pumps) as types of border guards control the incessant traffic of ions across cell membranes. Ion...

Automatic Sleep Staging Employing Convolutional Neural Networks and Cortical Connectivity Images.

IEEE transactions on neural networks and learning systems
Understanding of the neuroscientific sleep mechanisms is associated with mental/cognitive and physical well-being and pathological conditions. A prerequisite for further analysis is the identification of the sleep macroarchitecture through manual sle...