Molecular & cellular proteomics : MCP
Jun 26, 2019
Hypertrophic cardiomyopathy (HCM) is defined by pathological left ventricular hypertrophy (LVH). It is the commonest inherited cardiac condition and a significant number of high risk cases still go undetected until a sudden cardiac death (SCD) event....
Deep learning has shown remarkable improvements in the analysis of medical images without the need for engineered features. In this work, we hypothesize that deep learning is complementary to traditional feature estimation. We propose a network desig...
The establishment of new therapeutic strategies for metabolic syndrome is urgently needed because metabolic syndrome, which is characterized by several disorders, such as hypertension, increases the risk of lifestyle-related diseases. One approach is...
Biological psychiatry. Cognitive neuroscience and neuroimaging
Jun 21, 2019
BACKGROUND: The field of psychiatry has long sought biomarkers that can objectively diagnose patients, predict treatment response, or identify individuals at risk of illness onset. However, reliable psychiatric biomarkers have yet to emerge. The rece...
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
Jun 18, 2019
Amyloid A (AA) amyloidosis is found in humans and non-human primates, but quantifying disease risk prior to clinical symptoms is challenging. We applied machine learning to identify the best predictors of amyloidosis in rhesus macaques from availabl...
Computer methods and programs in biomedicine
Jun 17, 2019
BACKGROUND AND OBJECTIVE: The leading cause of vision loss in the Western World is Age-related Macular Degeneration (AMD), but together with modern medicines, tracking the number of Hyperreflective Foci (HF) on Optical Coherence Tomography (OCT) imag...
European journal of nuclear medicine and molecular imaging
Jun 15, 2019
Artificial intelligence (AI) is currently regaining enormous interest due to the success of machine learning (ML), and in particular deep learning (DL). Image analysis, and thus radiomics, strongly benefits from this research. However, effectively an...
BACKGROUND: Owing to the large variation in treatment response among patients with high-risk prostate cancer, it would be of value to use objective tools to monitor the status of bone metastases during clinical trials. Automated Bone Scan Index (aBSI...
Longitudinal imaging biomarkers are invaluable for understanding the course of neurodegeneration, promising the ability to track disease progression and to detect disease earlier than cross-sectional biomarkers. To properly realize their potential, b...
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