BACKGROUND: Pulmonary infections, ranging from mild respiratory issues to severe multiorgan failure, pose a major global health threat. The immune response in community-acquired pneumonia (CAP) and COVID-19 influences disease severity and outcomes, b...
Background Mitochondrial-related genes (MRGs) and programmed cell death-related genes (PCD-RGs) have been proven to play important roles in obsessive-compulsive disorder (OCD), and identifying their shared biomarkers is conducive to the diagnosis and...
Polycystic ovary syndrome (PCOS), a common endocrine condition affecting multiple systems, is tied to atherosclerosis (AS) progression among reproductive-aged women. The present study aimed to explore the underlying associations and uncover potential...
The human microbiome is pivotal in maintaining health and managing diseases. By examining the core microbiome in intensive care units (ICU) patients with pneumonia, we can gain valuable insights into the microbial communities associated with disease ...
Diabetic retinopathy is a leading cause of vision impairment globally. Disorganization of the retinal inner layers (DRIL), detected via optical coherence tomography, has emerged as a potential biomarker of disease severity and visual prognosis. This ...
Cardiovascular disease progression is characterised by the dysregulation of lipid metabolism and pro-atherogenic effects of adipose tissue signalling. Recent findings from the analysis of transcriptomic data in bulk tissue has enabled these insights ...
Improved biomarkers for predicting progression to active tuberculosis (TB) are urgently needed, especially in people with HIV, who are at elevated risk. We used high-throughput plasma proteomics and machine learning to identify signatures associated ...
Heydari et al. present an intriguing study examining the role of three long non-coding RNAs (lncRNAs)-H19, taurine upregulated gene 1 (TUG1), and colorectal neoplasia differentially expressed (CRNDE)-in the context of Coronavirus Disease 2019 (COVID-...
Fragile X Syndrome (FXS) is a rare neurodevelopmental disorder caused by a trinucleotide repeat expansion on the 5' untranslated region of the FMR1 gene. FXS is characterized by intellectual disability, anxiety, sensory hypersensitivity, and difficul...
INTRODUCTION: Retinal vein occlusion (RVO) represents a prevalent cause of vision impairment within retinal vascular diseases. Although hypoperfusion and inflammation are recognized pathogenic contributors, emerging evidence highlights oxidative stre...
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