BACKGROUND: Diabetic cardiomyopathy (DC) is a serious complication in patients with type 1 diabetes mellitus and has become a growing public health problem worldwide. There is evidence that endoplasmic reticulum stress (ERS) is involved in the pathog...
INTRODUCTION: The gut microbiota is associated with the response to immunotherapy in cutaneous melanoma (CM). However, gut fungal biomarkers and bacterial-fungal interactions have yet to be determined.
In recent years, machine learning-based handwriting analysis has emerged as a valuable tool for supporting the early diagnosis of Alzheimer's disease and predicting its progression. Traditional approaches represent handwriting tasks using a single fe...
Parkinson's disease, currently the fastest-growing neurodegenerative disorder globally, has seen a 50% increase in cases within just two years. As disease progression impairs speech, memory, and motor functions over time, early diagnosis is crucial f...
BACKGROUND: Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality globally. Traditional risk models, primarily based on established risk factors, often lack the precision needed to accurately predict new-onset major advers...
Psoriasis is a common chronic skin disorder with a polygenic background. It is widely acknowledged that Th17/IL-17A axis plays a key role in the pathogenesis of psoriasis. However, numerous regulatory genes upstream of the pathway remain undiscovered...
BACKGROUND: While ferroptosis has been recognised for its key role in tumour development, its involvement in DKD is not well understood. Identifying differentially expressed ferroptosis-related genes (DEIRGs) could help improve early diagnosis and tr...
Single-cell omics has emerged as a powerful tool for elucidating cellular heterogeneity in health and disease. Parallel advances in artificial intelligence (AI), particularly in pattern recognition, feature extraction and predictive modelling, now of...
ST-segment elevation myocardial infarction (STEMI) is considered a critical cardiac condition with a poor prognosis. Shortly after STEMI occurs, the increased number of circulating leukocytes including macrophages can lead to the accumulation of more...