AIMC Topic: Biosensing Techniques

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Directed Evolution of Fluorescent Genetically Encoded Biosensors: Innovative Approaches for Development and Optimization of Biosensors.

Chembiochem : a European journal of chemical biology
Fluorescent protein-based biosensors are indispensable molecular tools in cell biology and biomedical research, providing non-invasive dynamic measurements of metabolite concentrations and other cellular signals. Traditional methods for developing th...

Advancements in Circulating Tumor Cell Detection for Early Cancer Diagnosis: An Integration of Machine Learning Algorithms with Microfluidic Technologies.

Biosensors
Circulating tumor cells (CTCs) are vital indicators of metastasis and provide a non-invasive method for early cancer diagnosis, prognosis, and therapeutic monitoring. However, their low prevalence and heterogeneity in the bloodstream pose significant...

Nanopsychiatry: Advancing psychiatric diagnosis and monitoring through nanotechnology-based detection.

Clinica chimica acta; international journal of clinical chemistry
Nanopsychiatry, operating at the nanoscale, leverages engineered nanomaterials and nanodevices to revolutionize psychiatric diagnostics and therapeutics. This review systematically analyzes the implementation of advanced nanomaterials, including quan...

Fluorescence 'turn-on' sensing of glial fibrillary acidic protein using graphene oxide-quenched copper nanoclusters.

Mikrochimica acta
This study introduces a fluorescence based sensing platform made to detect glial fibrillary acidic protein (GFAP), a critical biomarker associated with glioblastoma and other astrocytic malignancies. Leveraging the unique optical properties of copper...

ZnO nanoflower-mediated paper-based electrochemical biosensor for perfect classification of cardiac biomarkers with physics-informed machine learning.

Mikrochimica acta
The widespread exposure of acute myocardial infarction globally demands an ultrasensitive, rapid, and cost-effective biosensor for troponin-I and T in a dynamic concentration range. Traditionally, the saturation of sensor response limits accurate pre...

A hybrid bioelectronic retina-probe interface for object recognition.

Biosensors & bioelectronics
Retina converts light stimuli into spike firings, encoding abundant visual information critical for both fundamental studies of the visual system and therapies for visual diseases. However, probing these spikes directly from the retina is hindered by...

Fusing Wearable Biosensors with Artificial Intelligence for Mental Health Monitoring: A Systematic Review.

Biosensors
The development of digital instruments for mental health monitoring using biosensor data from wearable devices can enable remote, longitudinal, and objective quantitative benchmarks. To survey developments and trends in this field, we conducted a sys...

Machine Learning-Assisted Portable Dual-Readout Biosensor for Visual Detection of Milk Allergen.

Nano letters
Beta-lactoglobulin (β-LG), the primary allergen in cow's milk, makes developing a rapid, sensitive, and convenient detection method essential for individuals with allergies. In this study, a graphdiyne-based self-powered electrochemical biosensor has...

Continuous real-time detection and management of comprehensive mental states using wireless soft multifunctional bioelectronics.

Biosensors & bioelectronics
Quantitatively measuring human mental states that profoundly affect cognition, behavior, and recovery would revolutionize personalized digital healthcare. Detecting fatigue, stress, and sleep is particularly important due to their interdependence: pe...

Electrochemical biosensing in oncology: a review advancements and prospects for cancer diagnosis.

Cancer biology & therapy
Early and precise diagnosis of cancer is pivotal for effective therapeutic intervention. Traditional diagnostic methods, despite their reliability, often face limitations such as invasiveness, high costs, labor-intensive procedures, extended processi...