Archives of pathology & laboratory medicine
Oct 1, 2025
CONTEXT.—: Distinguishing between renal oncocytic tumors, such as renal oncocytoma (RO), and a subset of tumors with overlapping characteristics, including the recently identified low-grade oncocytic tumor (LOT), can present a diagnostic challenge fo...
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Aug 10, 2025
PURPOSE: While immune checkpoint inhibition (ICI) has transformed the management of many advanced renal cell carcinomas (RCCs), the determinants of effective antitumor immunity for chromophobe RCC (ChRCC) and renal oncocytic tumors remain an unmet cl...
OBJECTIVE: The aim of this investigation is to assess the clinical usefulness of a machine learning model using contrast-enhanced ultrasound (CEUS) radiomics in discriminating clear cell renal cell carcinoma (ccRCC) from non-ccRCC.
OBJECTIVE: To evaluate and compare the diagnostic performance of CT texture analysis (CTTA), perfusion CT (PCT), and dual-energy CT (DECT) in distinguishing between clear-cell renal cell carcinoma (ccRCC) and non-ccRCC.
Journal of the American Society for Mass Spectrometry
Jun 4, 2025
In nontargeted spatial metabolomics, accurate annotation is crucial for understanding metabolites' biological roles and spatial patterns. MS mass spectrometry imaging (MSI) coverage is often incomplete or nonexistent, resulting in many unknown featur...
International journal of biological macromolecules
Jun 1, 2025
The pathogenesis of kidney cancer is not fully understood, so there is an urgent need to identify new biomarkers to improve diagnosis and treatment. The study identified KIF4A, TOP2A and ASPM as novel protein biomarkers for renal cancer and explored ...
BACKGROUND: Macrophages are closely associated with the progression of Kidney renal clear cell carcinoma (KIRC) and can influence programmed cell death (PCD) of tumour cells. To identify prognostic biomarkers for KIRC, it is essential to investigate ...
Kidney renal clear cell carcinoma (KIRC), a cancer characterized by substantial immune infiltration, exhibits limited sensitivity to conventional radiochemotherapy. Although immunotherapy has shown efficacy in some patients, its applicability is not ...
Fumarate hydratase-deficient renal cell carcinoma (FHdRCC) is a rare and aggressive form of kidney cancer that presents significant therapeutic challenges. Due to its rarity, treatment decisions often rely on comprehensive literature reviews to ident...
Single-cell sequencing has advanced our understanding of cellular heterogeneity and disease pathology, offering insights into cellular behavior and immune mechanisms. However, extracting meaningful phenotype-related features is challenging due to noi...
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