AIMC Topic: CD4-Positive T-Lymphocytes

Clear Filters Showing 21 to 27 of 27 articles

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.

Nucleic acids research Nov 29, 2016
The binding and contribution of transcription factors (TF) to cell specific gene expression is often deduced from open-chromatin measurements to avoid costly TF ChIP-seq assays. Thus, it is important to develop computational methods for accurate TF b...
Chromatin Assembly and Disassembly Human Embryonic Stem Cells Binding Sites Primary Cell Culture Humans Chromatin Machine Learning Algorithms DNA CD4-Positive T-Lymphocytes Hepatocytes K562 Cells Histones Hep G2 Cells Gene Expression Regulation Organ Specificity Cell Line Principal Component Analysis Cell Line, Tumor Protein Binding Transcription Factors
View on PubMed DOI

High-dimensional Immune Profiles and Machine Learning May Predict Acute Myeloid Leukemia Relapse Early following Transplant.

Journal of immunology (Baltimore, Md. : 1950) Nov 15, 2024
Identification of early immune signatures associated with acute myeloid leukemia (AML) relapse following hematopoietic stem cell transplant (HSCT) is critical for patient outcomes. We analyzed PBMCs from 58 patients with AML undergoing HSCT, focusing...
CD8-Positive T-Lymphocytes Leukemia, Myeloid, Acute Female Hematopoietic Stem Cell Transplantation Humans Aged CD4-Positive T-Lymphocytes Male Recurrence Machine Learning Adult Middle Aged Algorithms
View on PubMed DOI

High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status.

Cell reports Apr 13, 2021
Clinical definitions of asthma fail to capture the heterogeneity of immune dysfunction in severe, treatment-refractory disease. Applying mass cytometry and machine learning to bronchoalveolar lavage (BAL) cells, we find that corticosteroid-resistant ...
Humans Machine Learning Interleukin-10 Gene Expression Profiling Case-Control Studies Proteomics Signal Transduction Macrophages Asthma Severity of Illness Index Adrenal Cortex Hormones Immunologic Memory Gene Expression Regulation Anti-Asthmatic Agents Interleukin-7 Interferon-gamma Receptors, IgE Adaptive Immunity Bronchoalveolar Lavage Fluid Immunity, Innate CD8-Positive T-Lymphocytes CD4-Positive T-Lymphocytes
View on PubMed DOI

[Expression of follicular helper T cells in peripheral blood of patients with hepatic echinococcosis].

Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control Dec 25, 2018
OBJECTIVE: To detect the expression of follicuLar helper T cells (Tfh) and interleukin-21 (IL-21) in the peripheral blood of patients with hepatic echinococcosis and healthy controls, so as to explore the associations of Tfh and IL-21 expression with...
Flow Cytometry Humans Receptors, CXCR5 Case-Control Studies CD4-Positive T-Lymphocytes T-Lymphocytes, Helper-Inducer Interleukins Echinococcosis, Hepatic Interleukin-21
View on PubMed DOI

Characteristics of Long-term Nonprogressors and Viremia Controllers Infected with HIV-1 via Contaminated Blood Donations or Transfusions Conducted 20 Years Earlier.

Biomedical and environmental sciences : BES Dec 1, 2017
To characterize long-term nonprogressors (LTNPs) and viremia controllers (VCs), infected with HIV-1 through contaminated blood donation or transfusion between 1992 and 1996 in Henan, China. LTNPs and VCs were defined by CD4+T lymphocyte (CD4) count a...
Adolescent HIV Infections Viral Load Adult Male Middle Aged Humans CD4-Positive T-Lymphocytes Female Blood Transfusion HIV-1 Young Adult Blood Donors CD4 Lymphocyte Count Viremia
View on PubMed DOI

Feature selection using a one dimensional naïve Bayes' classifier increases the accuracy of support vector machine classification of CDR3 repertoires.

Bioinformatics (Oxford, England) Apr 1, 2017
MOTIVATION: Somatic DNA recombination, the hallmark of vertebrate adaptive immunity, has the potential to generate a vast diversity of antigen receptor sequences. How this diversity captures antigen specificity remains incompletely understood. In thi...
CD4-Positive T-Lymphocytes Complementarity Determining Regions Receptors, Antigen, T-Cell, alpha-beta Animals Support Vector Machine Databases, Genetic Mice, Inbred C57BL Bayes Theorem Humans Amino Acids
View on PubMed DOI

Control of HIV/AIDS infection system with drug dosages design via robust H(∞) fuzzy controller.

Bio-medical materials and engineering Jan 1, 2015
The designing of H∞ fuzzy controller for HIV/AIDS infected dynamic system has been considered in this paper. With TS fuzzy model and LMIs approach, the proposed controller is obtained for such a system. A set of sufficient conditions of the H∞ contro...
CD4-Positive T-Lymphocytes Drug Administration Schedule Drug Therapy, Computer-Assisted Treatment Outcome Fuzzy Logic CD4 Lymphocyte Count Feedback HIV Infections Anti-HIV Agents Humans
View on PubMed DOI
Popular Topics
Recent Journals