AIMC Topic: Chemoradiotherapy

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Machine learning for predicting pathological complete response in patients with locally advanced rectal cancer after neoadjuvant chemoradiotherapy.

Scientific reports
For patients with locally advanced rectal cancer (LARC), achieving a pathological complete response (pCR) after neoadjuvant chemoradiotherapy (CRT) provides them with the optimal prognosis. However, no reliable prediction model is presently available...

CT-based radiomic features to predict pathological response in rectal cancer: A retrospective cohort study.

Journal of medical imaging and radiation oncology
INTRODUCTION: Innovative biomarkers to predict treatment response in rectal cancer would be helpful in optimizing personalized treatment approaches. In this study, we aimed to develop and validate a CT-based radiomic imaging biomarker to predict path...

Deep learning-based radiomic features for improving neoadjuvant chemoradiation response prediction in locally advanced rectal cancer.

Physics in medicine and biology
Radiomic features achieve promising results in cancer diagnosis, treatment response prediction, and survival prediction. Our goal is to compare the handcrafted (explicitly designed) and deep learning (DL)-based radiomic features extracted from pre-tr...

Comparison of supervised machine learning classification techniques in prediction of locoregional recurrences in early oral tongue cancer.

International journal of medical informatics
BACKGROUND: The proper estimate of the risk of recurrences in early-stage oral tongue squamous cell carcinoma (OTSCC) is mandatory for individual treatment-decision making. However, this remains a challenge even for experienced multidisciplinary cent...

Machine learning for prediction of chemoradiation therapy response in rectal cancer using pre-treatment and mid-radiation multi-parametric MRI.

Magnetic resonance imaging
PURPOSE: To predict the neoadjuvant chemoradiation therapy (CRT) response in patients with locally advanced rectal cancer (LARC) using radiomics and deep learning based on pre-treatment MRI and a mid-radiation follow-up MRI taken 3-4 weeks after the ...

Prediction of response after chemoradiation for esophageal cancer using a combination of dosimetry and CT radiomics.

European radiology
PURPOSE: To investigate the treatment response prediction feasibility and accuracy of an integrated model combining computed tomography (CT) radiomic features and dosimetric parameters for patients with esophageal cancer (EC) who underwent concurrent...