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Chemoradiotherapy

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Comparison of supervised machine learning classification techniques in prediction of locoregional recurrences in early oral tongue cancer.

International journal of medical informatics
BACKGROUND: The proper estimate of the risk of recurrences in early-stage oral tongue squamous cell carcinoma (OTSCC) is mandatory for individual treatment-decision making. However, this remains a challenge even for experienced multidisciplinary cent...

Evaluation of Prognosis in Nasopharyngeal Cancer Using Machine Learning.

Technology in cancer research & treatment
BACKGROUND AND AIM: Although the prognosis of nasopharyngeal cancer largely depends on a classification based on the tumor-lymph node metastasis staging system, patients at the same stage may have different clinical outcomes. This study aimed to eval...

CT-based radiomic features to predict pathological response in rectal cancer: A retrospective cohort study.

Journal of medical imaging and radiation oncology
INTRODUCTION: Innovative biomarkers to predict treatment response in rectal cancer would be helpful in optimizing personalized treatment approaches. In this study, we aimed to develop and validate a CT-based radiomic imaging biomarker to predict path...

Deep learning-based radiomic features for improving neoadjuvant chemoradiation response prediction in locally advanced rectal cancer.

Physics in medicine and biology
Radiomic features achieve promising results in cancer diagnosis, treatment response prediction, and survival prediction. Our goal is to compare the handcrafted (explicitly designed) and deep learning (DL)-based radiomic features extracted from pre-tr...

Machine learning for predicting pathological complete response in patients with locally advanced rectal cancer after neoadjuvant chemoradiotherapy.

Scientific reports
For patients with locally advanced rectal cancer (LARC), achieving a pathological complete response (pCR) after neoadjuvant chemoradiotherapy (CRT) provides them with the optimal prognosis. However, no reliable prediction model is presently available...

System for High-Intensity Evaluation During Radiation Therapy (SHIELD-RT): A Prospective Randomized Study of Machine Learning-Directed Clinical Evaluations During Radiation and Chemoradiation.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
PURPOSE: Patients undergoing outpatient radiotherapy (RT) or chemoradiation (CRT) frequently require acute care (emergency department evaluation or hospitalization). Machine learning (ML) may guide interventions to reduce this risk. There are limited...