AIMC Topic: Datasets as Topic

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Pretraining model for biological sequence data.

Briefings in functional genomics
With the development of high-throughput sequencing technology, biological sequence data reflecting life information becomes increasingly accessible. Particularly on the background of the COVID-19 pandemic, biological sequence data play an important r...

Synthetic data in machine learning for medicine and healthcare.

Nature biomedical engineering
The proliferation of synthetic data in artificial intelligence for medicine and healthcare raises concerns about the vulnerabilities of the software and the challenges of current policy.

TERL: classification of transposable elements by convolutional neural networks.

Briefings in bioinformatics
Transposable elements (TEs) are the most represented sequences occurring in eukaryotic genomes. Few methods provide the classification of these sequences into deeper levels, such as superfamily level, which could provide useful and detailed informati...

Beware of the generic machine learning-based scoring functions in structure-based virtual screening.

Briefings in bioinformatics
Machine learning-based scoring functions (MLSFs) have attracted extensive attention recently and are expected to be potential rescoring tools for structure-based virtual screening (SBVS). However, a major concern nowadays is whether MLSFs trained for...

iPiDi-PUL: identifying Piwi-interacting RNA-disease associations based on positive unlabeled learning.

Briefings in bioinformatics
Accumulated researches have revealed that Piwi-interacting RNAs (piRNAs) are regulating the development of germ and stem cells, and they are closely associated with the progression of many diseases. As the number of the detected piRNAs is increasing ...

Retinal photograph-based deep learning algorithms for myopia and a blockchain platform to facilitate artificial intelligence medical research: a retrospective multicohort study.

The Lancet. Digital health
BACKGROUND: By 2050, almost 5 billion people globally are projected to have myopia, of whom 20% are likely to have high myopia with clinically significant risk of sight-threatening complications such as myopic macular degeneration. These are diagnose...

Modeling multi-species RNA modification through multi-task curriculum learning.

Nucleic acids research
N6-methyladenosine (m6A) is the most pervasive modification in eukaryotic mRNAs. Numerous biological processes are regulated by this critical post-transcriptional mark, such as gene expression, RNA stability, RNA structure and translation. Recently, ...

Merged Affinity Network Association Clustering: Joint multi-omic/clinical clustering to identify disease endotypes.

Cell reports
Although clinical and laboratory data have long been used to guide medical practice, this information is rarely integrated with multi-omic data to identify endotypes. We present Merged Affinity Network Association Clustering (MANAclust), a coding-fre...

Applying artificial intelligence in the microbiome for gastrointestinal diseases: A review.

Journal of gastroenterology and hepatology
For a long time, gut bacteria have been recognized for their important roles in the occurrence and progression of gastrointestinal diseases like colorectal cancer, and the ever-increasing amounts of microbiome data combined with other high-quality cl...

Deep learning meets metabolomics: a methodological perspective.

Briefings in bioinformatics
Deep learning (DL), an emerging area of investigation in the fields of machine learning and artificial intelligence, has markedly advanced over the past years. DL techniques are being applied to assist medical professionals and researchers in improvi...