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Disease Progression

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Keratoconus detection using deep learning of colour-coded maps with anterior segment optical coherence tomography: a diagnostic accuracy study.

BMJ open
OBJECTIVE: To evaluate the diagnostic accuracy of keratoconus using deep learning of the colour-coded maps measured with the swept-source anterior segment optical coherence tomography (AS-OCT).

Individualized prediction of depressive disorder in the elderly: A multitask deep learning approach.

International journal of medical informatics
INTRODUCTION: Depressive disorder is one of the major public health problems among the elderly. An effective depression risk prediction model can provide insights on the disease progression and potentially inform timely targeted interventions. Theref...

Using path signatures to predict a diagnosis of Alzheimer's disease.

PloS one
The path signature is a means of feature generation that can encode nonlinear interactions in data in addition to the usual linear terms. It provides interpretable features and its output is a fixed length vector irrespective of the number of input p...

CT Texture Analysis and Machine Learning Improve Post-ablation Prognostication in Patients with Adrenal Metastases: A Proof of Concept.

Cardiovascular and interventional radiology
INTRODUCTION: To assess the performance of pre-ablation computed tomography texture features of adrenal metastases to predict post-treatment local progression and survival in patients who underwent ablation using machine learning as a prediction tool...

Predicting PET-derived demyelination from multimodal MRI using sketcher-refiner adversarial training for multiple sclerosis.

Medical image analysis
Multiple sclerosis (MS) is the most common demyelinating disease. In MS, demyelination occurs in the white matter of the brain and in the spinal cord. It is thus essential to measure the tissue myelin content to understand the physiopathology of MS, ...

Radiomics features on non-contrast computed tomography predict early enlargement of spontaneous intracerebral hemorrhage.

Clinical neurology and neurosurgery
OBJECTIVE: To explore the value of radiomics features on non-contrast computed tomography (NCCT) in predicting early enlargement of spontaneous intracerebral hemorrhage (SICH).

Artificial intelligence predicts the progression of diabetic kidney disease using big data machine learning.

Scientific reports
Artificial intelligence (AI) is expected to support clinical judgement in medicine. We constructed a new predictive model for diabetic kidney diseases (DKD) using AI, processing natural language and longitudinal data with big data machine learning, b...

Learning to Quantify Emphysema Extent: What Labels Do We Need?

IEEE journal of biomedical and health informatics
Accurate assessment of pulmonary emphysema is crucial to assess disease severity and subtype, to monitor disease progression, and to predict lung cancer risk. However, visual assessment is time-consuming and subject to substantial inter-rater variabi...

Variation in the Thickness of Knee Cartilage. The Use of a Novel Machine Learning Algorithm for Cartilage Segmentation of Magnetic Resonance Images.

The Journal of arthroplasty
BACKGROUND: The variation in articular cartilage thickness (ACT) in healthy knees is difficult to quantify and therefore poorly documented. Our aims are to (1) define how machine learning (ML) algorithms can automate the segmentation and measurement ...