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Disease Progression

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Response to repeat echoendoscopic celiac plexus neurolysis in pancreatic cancer patients: A machine learning approach.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
BACKGROUND: /Objectives: Efficacy of repeat echoendoscopic celiac plexus neurolysis is still unclear. Aim of the study was to assess the efficacy of repeat celiac plexus neurolysis and to build an artificial neural network model able to predict pain ...

Residual convolutional neural network for predicting response of transarterial chemoembolization in hepatocellular carcinoma from CT imaging.

European radiology
BACKGROUND: We attempted to train and validate a model of deep learning for the preoperative prediction of the response of patients with intermediate-stage hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE).

Augmented intelligence with natural language processing applied to electronic health records for identifying patients with non-alcoholic fatty liver disease at risk for disease progression.

International journal of medical informatics
OBJECTIVE: Electronic health record (EHR) systems contain structured data (such as diagnostic codes) and unstructured data (clinical documentation). Clinical insights can be derived from analyzing both. The use of natural language processing (NLP) al...

Machine learning approaches to predict lupus disease activity from gene expression data.

Scientific reports
The integration of gene expression data to predict systemic lupus erythematosus (SLE) disease activity is a significant challenge because of the high degree of heterogeneity among patients and study cohorts, especially those collected on different mi...

Optimized machine learning methods for prediction of cognitive outcome in Parkinson's disease.

Computers in biology and medicine
BACKGROUND: Given the increasing recognition of the significance of non-motor symptoms in Parkinson's disease, we investigate the optimal use of machine learning methods for the prediction of the Montreal Cognitive Assessment (MoCA) score at year 4 f...

Identifying pre-disease signals before metabolic syndrome in mice by dynamical network biomarkers.

Scientific reports
The establishment of new therapeutic strategies for metabolic syndrome is urgently needed because metabolic syndrome, which is characterized by several disorders, such as hypertension, increases the risk of lifestyle-related diseases. One approach is...

Studying the Manifold Structure of Alzheimer's Disease: A Deep Learning Approach Using Convolutional Autoencoders.

IEEE journal of biomedical and health informatics
Many classical machine learning techniques have been used to explore Alzheimer's disease (AD), evolving from image decomposition techniques such as principal component analysis toward higher complexity, non-linear decomposition algorithms. With the a...

A deep learning model for early prediction of Alzheimer's disease dementia based on hippocampal magnetic resonance imaging data.

Alzheimer's & dementia : the journal of the Alzheimer's Association
INTRODUCTION: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia.