AIMC Topic: Disease Progression

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Use of Deep Learning for Detailed Severity Characterization and Estimation of 5-Year Risk Among Patients With Age-Related Macular Degeneration.

JAMA ophthalmology Dec 1, 2018
IMPORTANCE: Although deep learning (DL) can identify the intermediate or advanced stages of age-related macular degeneration (AMD) as a binary yes or no, stratified gradings using the more granular Age-Related Eye Disease Study (AREDS) 9-step detaile...
Risk Factors Aged Male Middle Aged Risk Assessment Humans Algorithms Retrospective Studies Female Reproducibility of Results United States Follow-Up Studies Macular Degeneration Diagnostic Techniques, Ophthalmological Macula Lutea Disease Progression Severity of Illness Index Deep Learning Incidence Time Factors
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Risk factors for diastolic left ventricular myocardial dysfunction in patients with chronic kidney disease.

Terapevticheskii arkhiv Sep 20, 2018
AIM: To examine the frequency and risk factors for the development of diastolic dysfunction (DD) of the left ventricle (LV) of the heart in patients with chronic kidney disease (CKD).
Glomerular Filtration Rate Russia Echocardiography Humans Cystatin C Middle Aged Hypertrophy, Left Ventricular Patient Acuity Female Disease Progression Ventricular Remodeling Risk Factors Ventricular Dysfunction, Left Incidence Male Renal Insufficiency, Chronic
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Prediction of Individual Disease Conversion in Early AMD Using Artificial Intelligence.

Investigative ophthalmology & visual science Jul 2, 2018
PURPOSE: While millions of individuals show early age-related macular degeneration (AMD) signs, yet have excellent vision, the risk of progression to advanced AMD with legal blindness is highly variable. We suggest means of artificial intelligence to...
Male Middle Aged Disease Progression Tomography, Optical Coherence Double-Blind Method Image Interpretation, Computer-Assisted Wet Macular Degeneration Machine Learning Retinal Drusen Prospective Studies Choroidal Neovascularization Female Geographic Atrophy Humans Aged Aged, 80 and over Artificial Intelligence
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Isometry Invariant Shape Descriptors for Abnormality Detection on Brain Surfaces Affected by Alzheimer's Disease.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Jul 1, 2018
Alzheimer's disease (AD), a progressive brain disorder, is the most common neurodegenerative disease in older adults. There is a need for brain structural magnetic resonance imaging (MRI) biomarkers to help assess AD progression and intervention effe...
Humans Middle Aged Disease Progression Cognitive Dysfunction Support Vector Machine Magnetic Resonance Imaging Biomarkers Brain Female Aged Male Brain Mapping Alzheimer Disease
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Retinal Nerve Fiber Layer Features Identified by Unsupervised Machine Learning on Optical Coherence Tomography Scans Predict Glaucoma Progression.

Investigative ophthalmology & visual science Jun 1, 2018
PURPOSE: To apply computational techniques to wide-angle swept-source optical coherence tomography (SS-OCT) images to identify novel, glaucoma-related structural features and improve detection of glaucoma and prediction of future glaucomatous progres...
Visual Field Tests Optic Nerve Diseases Glaucoma, Open-Angle Tonometry, Ocular Tomography, Optical Coherence Nerve Fibers Optic Disk Retinal Ganglion Cells Retrospective Studies Female Aged Adult Intraocular Pressure Male Humans Middle Aged Disease Progression Unsupervised Machine Learning Principal Component Analysis
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A probabilistic pathway score (PROPS) for classification with applications to inflammatory bowel disease.

Bioinformatics (Oxford, England) Mar 15, 2018
SUMMARY: Gene-based supervised machine learning classification models have been widely used to differentiate disease states, predict disease progression and determine effective treatment options. However, many of these classifiers are sensitive to no...
Metabolic Networks and Pathways Crohn Disease Models, Biological Supervised Machine Learning Gene Regulatory Networks Computational Biology Colitis, Ulcerative Diagnosis, Differential Humans Adult Disease Progression Child Protein Interaction Maps
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Research digest: progress in microvascular complications.

The lancet. Diabetes & endocrinology Feb 1, 2018
Prevalence Severity of Illness Index Diabetes Mellitus, Type 2 Diabetic Nephropathies Diabetic Angiopathies Humans Diabetic Retinopathy Machine Learning Risk Factors Disease Progression
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Multi-task fused sparse learning for mild cognitive impairment identification.

Technology and health care : official journal of the European Society for Engineering and Medicine Jan 1, 2018
BACKGROUND: Brain functional connectivity network (BFCN) has been widely applied to identify biomarkers for the brain function understanding and brain diseases analysis.
Image Processing, Computer-Assisted Support Vector Machine Magnetic Resonance Imaging Databases, Factual Biomarkers Humans Brain Algorithms Disease Progression Cognitive Dysfunction
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A Clinically-Translatable Machine Learning Algorithm for the Prediction of Alzheimer's Disease Conversion in Individuals with Mild and Premild Cognitive Impairment.

Journal of Alzheimer's disease : JAD Jan 1, 2018
BACKGROUND: Available therapies for Alzheimer's disease (AD) can only alleviate and delay the advance of symptoms, with the greatest impact eventually achieved when provided at an early stage. Thus, early identification of which subjects at high risk...
Aged Aged, 80 and over Sensitivity and Specificity Male Disease Progression Cognitive Dysfunction Logistic Models Support Vector Machine Magnetic Resonance Imaging Regression Analysis Machine Learning Algorithms Brain Prognosis Female Humans Predictive Value of Tests Area Under Curve Alzheimer Disease Neuropsychological Tests Atrophy
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Chronic Kidney Disease: Detection and Evaluation.

American family physician Dec 15, 2017
Chronic kidney disease affects 47 million people in the United States and is associated with significant health care costs, morbidity, and mortality. Because this disease can silently progress to advanced stages, early detection is critical for initi...
Risk Assessment Disease Progression Severity of Illness Index Renal Insufficiency, Chronic Glomerular Filtration Rate Humans Female Biomarkers Creatinine Risk Factors Prognosis Referral and Consultation Adult Practice Guidelines as Topic Male
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