AIMC Topic: DNA, Bacterial
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Predictive biophysical neural network modeling of a compendium of in vivo transcription factor DNA binding profiles for Escherichia coli.
Nature communications
May 7, 2025
The DNA binding of most Escherichia coli Transcription Factors (TFs) has not been comprehensively mapped, and few have models that can quantitatively predict binding affinity. We report the global mapping of in vivo DNA binding for 139 E. coli TFs us...
Accurate prediction of absolute prokaryotic abundance from DNA concentration.
Cell reports methods
Apr 28, 2025
Quantification of the absolute microbial abundance in a human stool sample is crucial for a comprehensive understanding of the microbial ecosystem, but this information is lost upon metagenomic sequencing. While several methods exist to measure absol...
Clinical evaluation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections: a prospective study.
Frontiers in cellular and infection microbiology
Jan 16, 2025
BACKGROUND: Though droplet digital PCR (ddPCR) has emerged as a promising tool for early pathogen detection in bloodstream infections (BSIs), more studies are needed to support its clinical application widely due to different ddPCR platforms with dis...
Optimizing the production and efficacy of antimicrobial bioactive compounds from in combating multi-drug-resistant pathogens.
Frontiers in cellular and infection microbiology
Jan 6, 2025
BACKGROUND: The rise of antibiotic-resistant pathogens has intensified the search for novel antimicrobial agents. This study aimed to isolate from local soil samples and evaluate its antimicrobial properties, along with optimizing the production of ...
Culture Media
Candida albicans
Staphylococcus aureus
Anti-Infective Agents
Bacillus subtilis
Anti-Bacterial Agents
Escherichia coli
Microbial Sensitivity Tests
Spectroscopy, Fourier Transform Infrared
Streptomyces
Drug Resistance, Multiple, Bacterial
Soil Microbiology
DNA, Bacterial
RNA, Ribosomal, 16S
Gut microbial composition associated with risk of premature aging in women with Yin-deficiency constitution.
Frontiers in cellular and infection microbiology
Jan 3, 2025
BACKGROUND: Yin-deficiency constitution (YinDC) refers to a traditional Chinese medicine concept, characterized by an imbalance state that includes an imbalance in the gut microbiota, resulting from a relative deficiency of Yin fluids within the body...
A drop dispenser for simplifying on-farm detection of foodborne pathogens.
PloS one
Dec 31, 2024
Nucleic-acid biosensors have emerged as useful tools for on-farm detection of foodborne pathogens on fresh produce. Such tools are specifically designed to be user-friendly so that a producer can operate them with minimal training and in a few simple...
Comparative analysis of the human microbiome from four different regions of China and machine learning-based geographical inference.
mSphere
Dec 19, 2024
The human microbiome, the community of microorganisms that reside on and inside the human body, is critically important for health and disease. However, it is influenced by various factors and may vary among individuals residing in distinct geographi...
Bacterial profile-based body fluid identification using a machine learning approach.
Genes & genomics
Nov 6, 2024
BACKGROUND: Identifying the origins of biological traces is critical for the reconstruction of crime scenes in forensic investigations. Traditional methods for body fluid identification rely on chemical, enzymatic, immunological, and spectroscopic te...
Machine learning supported single-stranded DNA sensor array for multiple foodborne pathogenic and spoilage bacteria identification in milk.
Food chemistry
Sep 6, 2024
Ensuring food safety through rapid and accurate detection of pathogenic bacteria in food products is a critical challenge in the food supply chain. In this study, a non-specific optical sensor array was proposed for the identification of multiple pat...
A culture-independent approach, supervised machine learning, and the characterization of the microbial community composition of coastal areas across the Bay of Bengal and the Arabian Sea.
BMC microbiology
May 10, 2024
BACKGROUND: Coastal areas are subject to various anthropogenic and natural influences. In this study, we investigated and compared the characteristics of two coastal regions, Andhra Pradesh (AP) and Goa (GA), focusing on pollution, anthropogenic acti...
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