AIMC Topic: Early Detection of Cancer

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Artificial Intelligence in cancer epigenomics: a review on advances in pan-cancer detection and precision medicine.

Epigenetics & chromatin
DNA methylation is a fundamental epigenetic modification that regulates gene expression and maintains genomic stability. Consequently, DNA methylation remains a key biomarker in cancer research, playing a vital role in diagnosis, prognosis, and tailo...

Challenges and Opportunities for Global Cervical Cancer Elimination: How Can We Build a Model for Other Cancers?

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
Cervical cancer remains a leading cause of cancer-related death among women globally, despite the availability of effective prevention through human papillomavirus (HPV) vaccination and HPV-based screening. This review explores the state-of-the-art t...

A hybrid GAN-based deep learning framework for thermogram-based breast cancer detection.

Scientific reports
Breast cancer remains one of the most prevalent and life-threatening diseases among women worldwide, necessitating early and accurate detection methods. Traditional diagnostic approaches often face limitations in sensitivity and specificity, highligh...

Development and Validation of a Lifestyle-Based 10-Year Risk Prediction Model of Colorectal Cancer for Early Stratification: Evidence from a Longitudinal Screening Cohort in China.

Nutrients
Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, with growing evidence linking risk to lifestyle and dietary factors. However, nutrition-related exposures have rarely been integrated into existing CRC ...

Molecular detection of hrHPV-induced high-grade squamous intraepithelial lesions of the cervix through a targeted RNA next generation sequencing assay.

Molecular medicine (Cambridge, Mass.)
BACKGROUND: Cervical cancer screening programs are increasingly relying on sensitive molecular approaches as primary tests to detect high-risk human papillomaviruses (hrHPV), the causative agents of cervix cancer. Although hrHPV infection is a pre-re...

Current status, hotspots, and trends in cancer prevention, screening, diagnosis, treatment, and rehabilitation: A bibliometric analysis.

Oncology research
OBJECTIVES: Decades of clinical and fundamental research advancements in oncology have led to significant breakthroughs such as early screening, targeted therapies, and immunotherapy, contributing to reduced mortality rates in cancer patients. Despit...

Improving cancer detection through computer-aided diagnosis: A comprehensive analysis of nonlinear and texture features in breast thermograms.

PloS one
Breast cancer is a significant health issue for women, characterized by its high rates of mortality and sickness. However, its early detection is crucial for improving patient outcomes. Thermography, which measures temperature variations between heal...

China Protocol for early screening, precise diagnosis, and individualized treatment of lung cancer.

Signal transduction and targeted therapy
Early screening, diagnosis, and treatment of lung cancer are pivotal in clinical practice since the tumor stage remains the most dominant factor that affects patient survival. Previous initiatives have tried to develop new tools for decision-making o...

Synthesizing [F]PSMA-1007 PET bone images from CT images with GAN for early detection of prostate cancer bone metastases: a pilot validation study.

BMC cancer
BACKGROUND: [F]FDG PET/CT scan combined with [F]PSMA-1007 PET/CT scan is commonly conducted for detecting bone metastases in prostate cancer (PCa). However, it is expensive and may expose patients to more radiation hazards. This study explores deep l...

Identification of a panel of volatile organic compounds in urine for early detection of for bladder cancer.

Scientific reports
The absence of specific markers makes early detection of bladder cancer (BC) challenging. Recent studies have reported the reliable diagnostic significance of volatile organic compounds (VOCs) in several cancers. This study aimed to investigate wheth...