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Non-invasive derivation of instantaneous free-wave ratio from invasive coronary angiography using a new deep learning artificial intelligence model and comparison with human operators' performance.

The international journal of cardiovascular imaging
Invasive coronary physiology is underused and carries risks/costs. Artificial Intelligence (AI) might enable non-invasive physiology from invasive coronary angiography (CAG), possibly outperforming humans, but has seldom been explored, especially for...

Dementia Overdiagnosis in Younger, Higher Educated Individuals Based on MMSE Alone: Analysis Using Deep Learning Technology.

Journal of Korean medical science
BACKGROUND: Dementia is a multifaceted disorder that affects cognitive function, necessitating accurate diagnosis for effective management and treatment. Although the Mini-Mental State Examination (MMSE) is widely used to assess cognitive impairment,...

Overconfident, but angry at least. AI-Based investigation of facial emotional expressions and self-assessment bias in human adults.

BMC psychology
Metacognition and facial emotional expressions both play a major role in human social interactions [1, 2] as inner narrative and primary communicational display, and both are limited by self-monitoring, control and their interaction with personal and...

A CT-based interpretable deep learning signature for predicting PD-L1 expression in bladder cancer: a two-center study.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: To construct and assess a deep learning (DL) signature that employs computed tomography imaging to predict the expression status of programmed cell death ligand 1 in patients with bladder cancer (BCa).

Development of a deep learning-based model for guiding a dissection during robotic breast surgery.

Breast cancer research : BCR
BACKGROUND: Traditional surgical education is based on observation and assistance in surgical practice. Recently introduced deep learning (DL) techniques enable the recognition of the surgical view and automatic identification of surgical landmarks. ...

Advancing AI-driven thematic analysis in qualitative research: a comparative study of nine generative models on Cutaneous Leishmaniasis data.

BMC medical informatics and decision making
BACKGROUND: As part of qualitative research, the thematic analysis is time-consuming and technical. The rise of generative artificial intelligence (A.I.), especially large language models, has brought hope in enhancing and partly automating thematic ...

Trans-ancestral rare variant association study with machine learning-based phenotyping for metabolic dysfunction-associated steatotic liver disease.

Genome biology
BACKGROUND: Genome-wide association studies (GWAS) have identified common variants associated with metabolic dysfunction-associated steatotic liver disease (MASLD). However, rare coding variant studies have been limited by phenotyping challenges and ...

Automated deep learning-based assessment of tumour-infiltrating lymphocyte density determines prognosis in colorectal cancer.

Journal of translational medicine
BACKGROUND: The presence of tumour-infiltrating lymphocytes (TILs) is a well-established prognostic biomarker across multiple cancer types, with higher TIL counts being associated with lower recurrence rates and improved patient survival. We aimed to...

Machine learning-assisted wearable sensing systems for speech recognition and interaction.

Nature communications
The human voice stands out for its rich information transmission capabilities. However, voice communication is susceptible to interference from noisy environments and obstacles. Here, we propose a wearable wireless flexible skin-attached acoustic sen...

Equitable machine learning counteracts ancestral bias in precision medicine.

Nature communications
Gold standard genomic datasets severely under-represent non-European populations, leading to inequities and a limited understanding of human disease. Therapeutics and outcomes remain hidden because we lack insights that could be gained from analyzing...